Exploiting donor-acceptor interactions in aqueous dynamic combinatorial libraries: exploratory studies of simple systems

被引：66

作者：

Au-Yeung, Ho Yu ^{[1
]}

Cougnon, Fabien B. L. ^{[1
]}

Otto, Sijbren ^{[2
]}

Pantos, G. Dan ^{[1
]}

Sanders, Jeremy K. M. ^{[1
]}

机构：

[1] Univ Cambridge, Univ Chem Lab, Cambridge CB2 1EW, England

[2] Univ Groningen, Stratingh Inst, Ctr Syst Chem, NL-9747 AG Groningen, Netherlands

来源：

CHEMICAL SCIENCE | 2010年 / 1卷 / 05期

基金：

英国工程与自然科学研究理事会;

关键词：

COVALENT CHEMISTRY; SELECTION; DRIVEN; AMPLIFICATION; RECOGNITION; RECEPTORS; MOLECULES; IDENTIFICATION; NAPHTHALENE; DISCOVERY;

D O I：

10.1039/c0sc00307g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The behaviour of aqueous dynamic combinatorial libraries (DCLs) containing either electron-rich donor building blocks based on dioxynaphthalene (DN), or electron-deficient acceptor building blocks based on naphthalenediimide (NDI) are described. The influence of concentration and ionic strength on library distribution and diversity, together with the responses to electronically-complementary templates have been explored in detail, establishing the principles to be employed in more complex libraries leading to a new generation of catenanes.

引用

页码：567 / 574

页数：8

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