Pathogenic variants in the human m6A reader YTHDC2 are associated with primary ovarian insufficiency

被引：0
|
作者：
McGlacken-Byrne, Sinead M. [1 ,2 ]
Torres, Ignacio Del Valle [1 ]
Stabej, Polona Le Quesne [3 ,4 ]
Belutti, Laura [5 ]
Ocaka, Louise [3 ]
Ishida, Miho [1 ]
Suntharalingham, Jenifer P. [1 ]
Dattani, Mehul T. [1 ]
Kelberman, Dan [3 ]
Lagos, Carlos F. [8 ,9 ]
Livera, Gabriel [5 ]
Conway, Gerard S. [2 ]
Achermann, John C. [1 ]
机构：
[1] UCL, UCL Great Ormond St Inst Child Hlth, Genet & Genom Med, London, England
[2] UCL, Inst Womens Hlth, London, England
[3] UCL, UCL Great Ormond St Inst Child Hlth, GOSgene, Genet & Genom Med, London, England
[4] Univ Auckland, Dept Mol Med & Pathol, Auckland, New Zealand
[5] Univ Paris Saclay, Univ Paris, UMR Genet Stabil Stem Cells & Radiat E008, Lab Dev Gonads,CEA, Paris, France
[6] UCL, Zayed Ctr Res Rare Dis Children, London, England
[7] UCL, UCL Great Ormond St Inst Child Hlth, Dev Biol & Canc, London, England
[8] Pontificia Univ Catolica Chile, Dept Endocrinol, Santiago, Chile
[9] Univ San Sebastian, Santiago, Chile
来源：
HORMONE RESEARCH IN PAEDIATRICS | 2021年 / 94卷 / SUPPL 1期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
P1-50
引用
收藏
页码：93 / 93
页数：1
相关论文
共 50 条
  • [21] The m6A reader YTHDC2 promotes the pathophysiology of temporal lobe epilepsy by modulating SLC7A11-dependent glutamate dysregulation in astrocytes
    Zhang, Kai
    Yang, Zhiquan
    Yang, Zhuanyi
    Du, Liangchao
    Zhou, Yu
    Fu, Shiyu
    Wang, Xiaoyue
    Li, Xing
    Liu, Dingyang
    He, Xinghu
    THERANOSTICS, 2024, 14 (14): : 5551 - 5570
  • [22] m6A in mRNA coding regions promotes translation via the RNA helicase-containing YTHDC2
    Mao, Yuanhui
    Dong, Leiming
    Liu, Xiao-Min
    Guo, Jiayin
    Ma, Honghui
    Shen, Bin
    Qian, Shu-Bing
    NATURE COMMUNICATIONS, 2019, 10 (1)
  • [23] Nuclear m6A Reader YTHDC1 Regulates mRNA Splicing
    Roundtree, Ian A.
    He, Chuan
    TRENDS IN GENETICS, 2016, 32 (06) : 320 - +
  • [24] Nuclear m6A Reader YTHDC1 Regulates mRNA Splicing
    Xiao, Wen
    Adhikari, Samir
    Dahal, Ujwal
    Chen, Yu-Sheng
    Hao, Ya-Juan
    Sun, Bao-Fa
    Sun, Hui-Ying
    Li, Ang
    Ping, Xiao-Li
    Lai, Wei-Yi
    Wang, Xing
    Ma, Hai-Li
    Huang, Chun-Min
    Yang, Ying
    Huang, Niu
    Jiang, Gui-Bin
    Wang, Hai-Lin
    Zhou, Qi
    Wang, Xiu-Jie
    Zhao, Yong-Liang
    Yang, Yun-Gui
    MOLECULAR CELL, 2016, 61 (04) : 507 - 519
  • [25] m6A Reader YTHDC2 Promotes Radiotherapy Resistance of Nasopharyngeal Carcinoma via Activating IGF1R/AKT/S6 Signaling Axis
    He, Jun-Ju
    Li, Zhi
    Rong, Zhuo-Xian
    Gao, Jie
    Mu, Yun
    Guan, Yi-Di
    Ren, Xin-Xin
    Zi, Yu-Yuan
    Liu, Li-Yu
    Fan, Qi
    Zhou, Ming
    Duan, Yu-Mei
    Zhou, Qin
    Deng, Yue-Zhen
    Sun, Lun-Quan
    FRONTIERS IN ONCOLOGY, 2020, 10
  • [26] Critical roles of mRNA m6A modification and YTHDC2 expression for meiotic initiation and progression in female germ cells
    Zeng, Ming
    Dai, Xin
    Liang, Zhibing
    Sun, Ruliang
    Huang, Sui
    Luo, Liangping
    Li, Zhongxiang
    GENE, 2020, 753
  • [27] The m6A reader YTHDC1-mediated lncRNA CTBP1-AS2 m6A modification accelerates cholangiocarcinoma progression
    Jin, Zhe
    Liu, Yahui
    HELIYON, 2023, 9 (09)
  • [28] Domain confusion 2: m6A-independent role of YTHDC2
    Larivera, Simone
    Meister, Gunter
    MOLECULAR CELL, 2022, 82 (09) : 1608 - 1609
  • [29] Protective role of m6A binding protein YTHDC2 on CCNB2 in manganese-induced spermatogenesis dysfunction
    Qi, Zhipeng
    Liu, Yanan
    Yang, Haibo
    Yang, Xinxin
    Wang, Haiying
    Liu, Bingchen
    Yuan, Yuan
    Wang, Gang
    Xu, Bin
    Liu, Wei
    Xu, Zhaofa
    Deng, Yu
    CHEMICO-BIOLOGICAL INTERACTIONS, 2022, 351
  • [30] The biological function of the N6-Methyladenosine reader YTHDC2 and its role in diseases
    Wu, Xudong
    Chen, Hui
    Li, Kai
    Zhang, Hong
    Li, Kai
    Tan, Haoyu
    JOURNAL OF TRANSLATIONAL MEDICINE, 2024, 22 (01)
12345