Ultrasonic assisted-silica mediated [3+2] cycloaddition of azomethine ylides - a facile multicomponent one-pot synthesis of novel dispiroheterocycles

被引：69
作者：
Babu, A. R. Suresh [1 ]
Raghunathan, R. [1 ]
机构：
[1] Univ Madras, Dept Organ Chem, Madras 600025, Tamil Nadu, India
来源：
TETRAHEDRON LETTERS | 2007年 / 48卷 / 38期
关键词：
D O I：
10.1016/j.tetlet.2007.07.085
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient synthesis of dispiro-oxindolopyrrolizidine and dispirooxindolothienopyrrole derivatives has been expediently accomplished via a one-pot, three-component 1,3-dipolar cycloaddition reaction. High regioselectivity was achieved on ultrasonication in the presence of silica as a catalyst. X-ray diffraction studies of one of the cycloadducts proved the structure and regiochemistry of the cycloaddition. (c) 2007 Elsevier Ltd. All rights reserved.
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收藏
页码：6809 / 6813
页数：5
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