Bioremediation of radionuclides: Emerging technologies

被引：16

作者：

Kumar, Raj ^{[1
]}

Singh, Sompal

Singh, Om V.

机构：

[1] Inst Nucl Med & Allied Sci, Div Radiat Biol & Radiat Protect, Radiat Biotechnol Unit, Delhi 110054, India

[2] Johns Hopkins Univ, Sch Med, Dept Pediat, Baltimore, MD 21205 USA

来源：

OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY | 2007年 / 11卷 / 03期

关键词：

D O I：

10.1089/omi.2007.0013

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A large quantity of radioactive waste is being generated as the byproduct of atomic energy and related programs worldwide. There are multiple radioactive waste dumping sites, that, if exposed to the general population, may cause serious life-threatening disorders. Currently, no efficient technology is available that can store the radioactive wastes with adequate safety. Therefore, bioremediation of radionuclides/radioactive waste is an unavoidable necessity that has been tried using biotransformation, bioaccumulation, biosorption, biostimulation, and bioaugmentaion, with limited success. Genetic engineering has been implemented to develop an organism that can effectively detoxify radionuclides along with other organic pollutants present as co-contaminants in the radioactive waste sites. However, the lack of system-wide information regarding factors regulating growth and metabolism of microbial communities can be conquered by newly seeded "-omics"-based technologies, viz. transcriptomics and proteomics. Studies combining functional transcriptomics and proteomics would create a system-wide approach studying the microbial metabolism in radionuclides detoxification.

引用

页码：295 / 304

页数：10

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