Reinfection cases by closely related SARS-CoV-2 lineages in Southern Brazil

被引：2

作者：

Gularte, Juliana Schons ^{[1
]}

da Silva, Mariana Soares ^{[1
]}

Demoliner, Meriane ^{[1
]}

Hansen, Alana Witt ^{[1
]}

Heldt, Fagner Henrique ^{[1
]}

Silveira, Flavio ^{[1
]}

Filippi, Micheli ^{[1
]}

Pereira, Vyctoria Malayhka de Abreu Goes ^{[1
]}

da Silva, Francini Pereira ^{[1
]}

Mallmann, Larissa ^{[1
]}

Fink, Pietra ^{[1
]}

Laux, Jessica Luisa ^{[1
]}

Weber, Matheus Nunes ^{[1
]}

de Almeida, Paula Rodrigues ^{[1
]}

Fleck, Juliane Deise ^{[1
]}

Spilki, Fernando Rosado ^{[1
]}

机构：

[1] Univ Feevale, Lab Microbiol Mol, Rodovia ERS-239,2755,Predio Vermelho,Piso 1,Sala, BR-93525075 Novo Hamburgo, RS, Brazil

来源：

BRAZILIAN JOURNAL OF MICROBIOLOGY | 2021年 / 52卷 / 04期

关键词：

Reinfection; COVID-19; B.1; Healthcare worker; Brazil;

D O I：

10.1007/s42770-021-00621-0

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the pandemic that started in late 2019 and still affects people's lives all over the world. Lack of protective immunity after primary infection has been involved with reported reinfection cases by SARS-CoV-2. In this study, we described two cases of reinfection caused by non-VOC (Variants of Concern) strains in southern Brazil, being one patient a healthcare worker. The four samples previously positive for SARS-CoV-2 by real-time quantitative reverse transcription polymerase chain reaction (RT-qPCR) were sequenced by a high-performance platform and the genomic analysis confirmed that lineages responsible for infections were B.1.91 and B.1.1.33 (patient 1), and B.1.1.33 and B.1.1.28 (patient 2). The interval between the two positive RT-qPCR for patients 1 and 2 was 45 and 61 days, respectively. This data shows that patients may be reinfected even by very closely related SARS-CoV-2 lineages.

引用

页码：1881 / 1885

页数：5

共 26 条

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