Enhancing the biocompatibility of Ti6Al4V implants by laser surface microtexturing: an in vitro study

被引：61

作者：

Mukherjee, S. ^{[1
]}

Dhara, S. ^{[2
]}

Saha, P. ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Mech Engn, Kharagpur 721302, W Bengal, India

[2] Indian Inst Technol, Sch Med Sci & Technol, Kharagpur 721302, W Bengal, India

来源：

INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TECHNOLOGY | 2015年 / 76卷 / 1-4期

关键词：

Ti6Al4V; Laser surface microtexturing; Biocompatibility; TITANIUM-ALLOYS; ORGANIZATION; TI-6AL-4V; BEHAVIOR; TISSUE; VIVO;

D O I：

10.1007/s00170-013-5277-2

中图分类号：

TP [自动化技术、计算机技术];

学科分类号：

0812 ;

摘要：

The biocompatibility of an implant material depends on the bulk physical properties as well as on the surface properties. Titanium alloy Ti6Al4V is a very popular biological implant material for its bulk physical properties resembling those of natural bone. It is possible to modify the surface properties of Ti6Al4V by laser irradiation. In the current study, using continuous wave fibre laser, grooves of different depths and widths have been created by varying laser power and scan speed. Laser frequency and duty cycle were varied to alter the inside surface topographies of the microgrooves. The surface wettability and the protein adsorption on the surface were found to be dependent on the microtexture parameters. To understand the effect of this type of texturing on the cell behaviour, MG63 cells have been cultured on the sample surfaces, and the result was studied after 3 and 5 days of cell culture. Surface features dimensionally closer to the cell dimensions are able to positively affect the viability and spreading of MG63 cells, as seen from this study.

引用

页码：5 / 15

页数：11

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