Flexible Organic Electrochemical Transistors for Highly Selective Enzyme Biosensors and Used for Saliva Testing

被引:298
作者
Liao, Caizhi [1 ]
Mak, Chunhin [1 ]
Zhang, Meng [1 ]
Chan, Helen L. W. [1 ]
Yan, Feng [1 ]
机构
[1] Hong Kong Polytech Univ, Dept Appl Phys, Kowloon, Hong Kong, Peoples R China
关键词
biosensors; enzymes; organic electrochemical transistors; selectivity; uric acid; FIELD-EFFECT TRANSISTOR; URIC-ACID; IN-VIVO; GATE ELECTRODES; GRAPHENE OXIDE; POLYANILINE; IMMOBILIZATION; PERFORMANCE; FABRICATION; SENSORS;
D O I
10.1002/adma.201404378
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Flexible organic electrochemical transistors (OECTs) are successfully used as high-performance enzyme biosensors, such as uric acid (UA) and cholesterol sensors. The sensitivity and selectivity of the sensors can be simultaneously enhanced by co-modifying the gate electrodes with positively/negatively charged bilayer polymer films and enzymes. These OECT-based UA sensors are successfully utilized for non-invasive UA detection in human saliva. (Figure Presented). © 2014 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:676 / 681
页数:6
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