Evolution of ESI-mass spectrometry and Fourier transform ion cyclotron resonance for proteomics and other biological applications

被引:66
|
作者
Smith, RD [1 ]
机构
[1] Pacific NW Natl Lab, Environm Mol Sci Lab, Richland, WA 99352 USA
基金
美国国家卫生研究院;
关键词
electrospray ionization; FTICR mass spectrometry; proteomics; capillary electrophoresis; proteins;
D O I
10.1016/S1387-3806(00)00352-3
中图分类号
O64 [物理化学(理论化学)、化学物理学]; O56 [分子物理学、原子物理学];
学科分类号
070203 ; 070304 ; 081704 ; 1406 ;
摘要
A perspective is presented centered on the author's contributions to developments involving electrospray ionization-mass spectrometry, capillary electrophoresis-mass spectrometry, and Fourier transform ion cyclotron resonance (FTICR) mass spectrometry and their applications to biological systems, with a special emphasis on the study of noncovalent complexes and proteomics. (C) 2000 Elsevier Science B.V.
引用
收藏
页码:509 / 544
页数:36
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