Targeting the TGFβ signaling network in human neoplasia

被引：212

作者：

Dumont, N

Arteaga, CL ^{[1
]}

机构：

[1] Vanderbilt Univ, Sch Med, Dept Canc Biol, Nashville, TN 37212 USA

[2] Vanderbilt Univ, Sch Med, Dept Med, Nashville, TN 37212 USA

[3] Vanderbilt Univ, Med Ctr, Vanderbilt Ingram Comprehens Canc Ctr, Breast Canc Res Program, Nashville, TN 37232 USA

来源：

CANCER CELL | 2003年 / 3卷 / 06期

关键词：

D O I：

10.1016/S1535-6108(03)00135-1

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

[No abstract available]

引用

页码：531 / 536

页数：6

共 50 条

[1]

Ananth S, 1999, CANCER RES, V59, P2210

[2]

ARTEAGA CL, 1993, CELL GROWTH DIFFER, V4, P193

[3] ANTI-TRANSFORMING GROWTH-FACTOR (TGF)-BETA ANTIBODIES INHIBIT BREAST-CANCER CELL TUMORIGENICITY AND INCREASE MOUSE SPLEEN NATURAL-KILLER-CELL ACTIVITY - IMPLICATIONS FOR A POSSIBLE ROLE OF TUMOR-CELL HOST TGF-BETA INTERACTIONS IN HUMAN BREAST-CANCER PROGRESSION [J].

ARTEAGA, CL ;

HURD, SD ;

WINNIER, AR ;

JOHNSON, MD ;

FENDLY, BM ;

FORBES, JT .

JOURNAL OF CLINICAL INVESTIGATION, 1993, 92 (06) :2569-2576

[4] Phosphatidylinositol 3-kinase function is required for transforming growth factor β-mediated epithelial to mesenchymal transition and cell migration [J].

Bakin, AV ;

Tomlinson, AK ;

Bhowmick, NA ;

Moses, HL ;

Arteaga, CL .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (47) :36803-36810

[5]

Bandyopadhyay A, 1999, CANCER RES, V59, P5041

[6]

Bandyopadhyay A, 2002, CANCER RES, V62, P4690

[7]

Böttinger EP, 1997, CANCER RES, V57, P5564

[8] TGF beta 1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice [J].

Cui, W ;

Fowlis, DJ ;

Bryson, S ;

Duffie, E ;

Ireland, H ;

Balmain, A ;

Akhurst, RJ .

CELL, 1996, 86 (04) :531-542

[9] TGF-β signaling in tumor suppression and cancer progression [J].

Derynck, R ;

Akhurst, RJ ;

Balmain, A .

NATURE GENETICS, 2001, 29 (02) :117-129

[10] Autocrine transforming growth factor-β signaling mediates smad-independent motility in human cancer cells [J].

Dumon, N ;

Bakin, AV ;

Arteaga, CL .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (05) :3275-3285

← 1 2 3 4 5 →