Development of a risk assessment tool for women with a family history of breast cancer

被引：30

作者：

Braithwaite, D

Sutton, S

Mackay, J

Stein, J

Emery, J

机构：

[1] Univ Calif San Francisco, Ctr Comprehens Canc, Carol Franck Buck Breast Care Ctr, San Francisco, CA 94115 USA

[2] Univ Cambridge, Dept Publ Hlth & Primary Care, Cambridge CB2 1TN, England

[3] Great Ormond St Hosp Sick Children, NE Thames Clin Genet Serv, Genet Unit, London WC1N 3JH, England

[4] Inst Child Hlth, London, England

[5] UCL Hosp, Dept Surg, Familial Breast Clin, London, England

[6] Univ Western Australia, Discipline Gen Practice, Perth, WA 6009, Australia

来源：

CANCER DETECTION AND PREVENTION | 2005年 / 29卷 / 05期

关键词：

breast cancer; BRCA1; BRCA2; risk assessnient; counseling; computer support; psychological impact; patient education; questionnaires; interventions; mammography; perceived benefits; risk perception; risk accuracy; cancer worry; genetic risk assessinent in the clinical environment (GRACE);

D O I：

10.1016/j.cdp.2005.06.001

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background: Innovative technologies that enable the collection of family history information and the assessment of breast cancer risk have a potential to enhance the quality of preventive care. We developed a computerized tool that supports stratification of breast cancer risk, genetic risk assessment in the clinical environment (GRACE). Methods: In a preliminary evaluation of the tool's impact, we randomized women with a family history of breast cancer (n = 72) to either use the GRACE tool or undergo risk counseling by a nurse specialist. Results: There was no statistically significant differences between the GRACE and nurse counselling groups in risk perceptions (F = .03 P > .05) and cancer-related worries (F = .80, P > .05). However, patients reported more positive attitudes toward working with the nurse. Conclusion: It was feasible to use GRACE in a Clinic. Additional research is required to identify solutions for providing emotional support in conjunction with the tool. (c) 2005 International Society for Preventive Oncology. Published by Elsevier Ltd. All rights reserved.

引用

页码：433 / 439

页数：7