Rod a-wave analysis using high intensity flashes adds information on rod system function in 25% of clinical ERG recordings

被引：8

作者：

Nilsson, Josefin ^{[1
,2
]}

Wright, Tom ^{[1
,2
]}

Westall, Carol A. ^{[2
,3
]}

机构：

[1] Univ Gothenburg, Sahlgrenska Acad, Dept Clin Neurophysiol, Gothenburg 41345, Sweden

[2] Hosp Sick Children, Visual Electrophysiol Unit, Toronto, ON M5G 1X8, Canada

[3] Univ Toronto, Dept Ophthalmol & Vis Sci, Toronto, ON M5S 1A1, Canada

来源：

VISION RESEARCH | 2008年 / 48卷 / 18期

关键词：

electroretinogram; photoreceptor; retinal development; rod dystrophy;

D O I：

10.1016/j.visres.2008.05.011

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Purpose: To investigate whether rod a-wave analysis using high intensity flashes adds information above that obtained with standard ERG. Methods: A total of 2396 eyes were recorded. Patient age was 2.4 months-84.6 years. Results: A-wave analysis of high intensity flashes provided additional information on rod system function in 25% of eyes recorded, most importantly in subjects with midretinal disease and artificially reduced rod responses. High intensity flashes also provided measurable responses for longitudinal monitoring in rod dystrophies with non-recordable rod ERGs. Conclusions: Clinical ERG testing would benefit greatly from adding high intensity flashes to its standard testing conditions. (c) 2008 Elsevier Ltd. All rights reserved.

引用

页码：1920 / 1925

页数：6

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