Definition of ALI/ARDS

被引:91
作者
Raghavendran, Krishnan [1 ]
Napolitano, Lena M. [1 ]
机构
[1] Univ Michigan Hlth Syst, Dept Surg, Div Acute Care Surg, Ann Arbor, MI 48109 USA
关键词
Acute respiratory distress syndrome; Acute lung injury; Respiratory failure; Terminology; RESPIRATORY-DISTRESS-SYNDROME; ACUTE LUNG INJURY; RANDOMIZED CONTROLLED-TRIAL; CENTRAL VENOUS CATHETER; SURGICAL-PATIENTS; IMPROVED OUTCOMES; INTENSIVE-CARE; TIDAL VOLUMES; CELL-DEATH; VENTILATION;
D O I
10.1016/j.ccc.2011.05.006
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Although acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are caused by different injuries and conditions, their similar clinical picture makes a compelling case for them to be studied as a single entity. An array of potential specific targets for pharmacologic intervention can be applied to ALI/ARDS as one disease. Although a working definition of ALI/ARDS that includes pulmonary and extrapulmonary causes can have benefit in standardizing supportive care, it can also complicate assessments of the efficacy of therapeutic interventions. In this article, definitions that have been recently used for ALI/ARDS in various clinical studies are discussed individually.
引用
收藏
页码:429 / +
页数:10
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