Osteoarthritis year 2010 in review: biochemical markers

被引:44
作者
Kraus, V. B. [1 ]
机构
[1] Duke Univ, Med Ctr, Div Rheumatol, Dept Med, Durham, NC 27278 USA
关键词
Osteoarthritis; Biomarkers; OLIGOMERIC MATRIX PROTEIN; SYNOVIAL-FLUID; KNEE OSTEOARTHRITIS; AGGRECAN FRAGMENTS; MONOCLONAL-ANTIBODIES; CARTILAGE DEGRADATION; BIOMARKERS; SERUM; CLEAVAGE; MODEL;
D O I
10.1016/j.joca.2011.02.002
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
At the 2010 Osteoarthritis Research Society International (OARS!) congress in Brussels I was asked to present on "Biochemical Markers" in the Year in Review" session. This provided an opportunity to summarize ongoing work and consensus building in the osteoarthritis research community related to osteoarthritis biomarkers, and second, and an opportunity to briefly overview a subset of studies from the previous 12 months related to soluble biomarkers that provided novel insights in the field. This review therefore briefly summarizes the progress in 2010 of the OARSI OA Biomarkers Global Initiative and the OARSI FDA Biomarkers Working Group, and provides a summary of selected osteoarthritis biomarker studies reported over the previous 12 months based on a review of articles from seven musculoskeletal journals and a PubMed search using the terms biomarkers and osteoarthritis. (C) 2011 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:346 / 353
页数:8
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