Organs at risk in the brain and their dose-constraints in adults and in children: A radiation oncologist's guide for delineation in everyday practice

被引：172

作者：

Scoccianti, Silvia ^{[1
]}

Detti, Beatrice ^{[1
]}

Gadda, Davide ^{[2
]}

Greto, Daniela ^{[1
]}

Furfaro, Ilaria ^{[1
]}

Meacci, Fiammetta ^{[1
]}

Simontacchi, Gabriele

Di Brina, Lucia ^{[1
]}

Bonomo, Pierluigi ^{[1
]}

Giacomelli, Irene ^{[1
]}

Meattini, Icro ^{[1
]}

Mangoni, Monica ^{[1
]}

Cappelli, Sabrina ^{[1
]}

Cassani, Sara ^{[1
]}

Talamonti, Cinzia ^{[3
]}

Bordi, Lorenzo ^{[4
]}

Livi, Lorenzo ^{[1
]}

机构：

[1] Azienda Univ, Osped Careggi, Radiat Oncol, Florence, Italy

[2] Azienda Univ, Osped Careggi, Neuroradiol Unit, Florence, Italy

[3] Azienda Univ, Osped Careggi, Med Phys, Florence, Italy

[4] Azienda Univ, Osped Careggi, Neurosurg, Florence, Italy

来源：

RADIOTHERAPY AND ONCOLOGY | 2015年 / 114卷 / 02期

关键词：

Radiotherapy atlas; Organs at risk; Brain contouring atlas; Normal tissue; Dose-constraints; Optic chiasm; INTENSITY-MODULATED RADIOTHERAPY; TARGET VOLUME DELINEATION; STEREOTACTIC RADIOTHERAPY; HIPPOCAMPAL AVOIDANCE; CRANIAL IRRADIATION; HEARING-LOSS; THERAPY; TUMORS; BOOST; CHEMOTHERAPY;

D O I：

10.1016/j.radonc.2015.01.016

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Purpose: Accurate organs at risk definition is essential for radiation treatment of brain tumors. The aim of this study is to provide a stepwise and simplified contouring guide to delineate the OARs in the brain as it would be done in the everyday practice of planning radiotherapy for brain cancer treatment. Methods: Anatomical descriptions and neuroimaging atlases of the brain were studied. The dosimetric constraints used in literature were reviewed. Results: A Computed Tomography and Magnetic Resonance Imaging based detailed atlas was developed jointly by radiation oncologists, a neuroradiologist and a neurosurgeon. For each organ brief anatomical notion, main radiological reference points and useful considerations are provided. Recommended dose-constraints both for adult and pediatric patients were also provided. Conclusions: This report provides guidelines for OARs delineation and their dose-constraints for the treatment planning of patients with brain tumors. (C) 2015 Elsevier Ireland Ltd. All rights reserved.

引用

页码：230 / 238

页数：9

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