Five novel oligostilbenes from the roots of Caragana sinica

被引：90

作者：

Luo, HF ^{[1
]}

Zhang, LP ^{[1
]}

Hu, CQ ^{[1
]}

机构：

[1] Fudan Univ, Sch Pharm, Dept Chem Nat Drugs, Shanghai 200032, Peoples R China

来源：

TETRAHEDRON | 2001年 / 57卷 / 23期

基金：

中国国家自然科学基金;

关键词：

Caragana sinica; leguminosae; caraphenol A; B; C; (+)-isoampelopsin F; (-)-ampelopsin F; oligostilbene; resveratrol; trimer; dimer;

D O I：

10.1016/S0040-4020(01)00427-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

One novel resveratrol trimer, caraphenol A (1), and four novel resveratrol dimers, (+)-isoampelopsin F (2), caraphenol B (3), C (4), (-)-ampelopsin F (5) were isolated from the roots of C. sinica. Their structures and stereochemistry were elucidated by means of spectroscopic evidence, especially HMBC and NOE experiments. The pharmacological activities in anti-HIV of all compounds and stimulation of osteoblast growth tests of the EtOAc extract of the roots of C. sinica have been determined. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：4849 / 4854

页数：6

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