MINT, the molecular interaction database: 2012 update

被引：746

作者：

Licata, Luana ^{[1
]}

Briganti, Leonardo ^{[1
]}

Peluso, Daniele ^{[2
]}

Perfetto, Livia ^{[1
]}

Iannuccelli, Marta ^{[1
]}

Galeota, Eugenia ^{[1
]}

Sacco, Francesca ^{[1
]}

Palma, Anita ^{[1
]}

Nardozza, Aurelio Pio ^{[1
]}

Santonico, Elena ^{[1
]}

Castagnoli, Luisa ^{[1
]}

Cesareni, Gianni ^{[1
,2
]}

机构：

[1] Univ Roma Tor Vergata, Dept Biol, I-00133 Rome, Italy

[2] IRCCS Fdn Santa Lucia, I-00143 Rome, Italy

来源：

NUCLEIC ACIDS RESEARCH | 2012年 / 40卷 / D1期

关键词：

D O I：

10.1093/nar/gkr930

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Molecular INTeraction Database (MINT, http://mint.bio.uniroma2.it/mint/) is a public repository for protein-protein interactions (PPI) reported in peer-reviewed journals. The database grows steadily over the years and at September 2011 contains approximately 235 000 binary interactions captured from over 4750 publications. The web interface allows the users to search, visualize and download interactions data. MINT is one of the members of the International Molecular Exchange consortium (IMEx) and adopts the Molecular Interaction Ontology of the Proteomics Standard Initiative (PSI-MI) standards for curation and data exchange. MINT data are freely accessible and downloadable at http://mint.bio.uniroma2.it/mint/download.do. We report here the growth of the database, the major changes in curation policy and a new algorithm to assign a confidence to each interaction.

引用

页码：D857 / D861

页数：5

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