Accelerated Pancreatobiliary MRI for Pancreatic Cancer Surveillance in Patients With Pancreatic Cystic Neoplasms

被引:3
|
作者
Yoon, Jeong Hee [1 ,2 ]
Bae, Jae Seok [1 ,2 ]
Jeon, Sunkyung [1 ,2 ]
Chang, Won [3 ]
Lee, Sang Min [4 ]
Park, Jin Young [5 ]
Lee, Jeong Sub [6 ]
Lee, Eun Sun [7 ]
Cho, In Rae [8 ]
Lee, Sang-Hyub [8 ]
Lee, Jeong Min [1 ,2 ,9 ]
机构
[1] Seoul Natl Univ Hosp, Dept Radiol, 101 Daehak Ro, Seoul 03080, South Korea
[2] Seoul Natl Univ, Dept Radiol, Coll Med, 103 Daehak Ro, Seoul 03087, South Korea
[3] Seoul Natl Univ, Dept Radiol, Bundang Hosp, Seongnam Si 13620, South Korea
[4] Hallym Univ, Sacred Heart Hosp, Dept Radiol, Anyang 14068, South Korea
[5] Inje Univ, Busan Paik Hosp, Dept Radiol, Bokji Ro 75, Busan 47392, South Korea
[6] Jeju Natl Univ Hosp, Dept Radiol, Jeju Si 63241, South Korea
[7] Chung Ang Univ Hosp, Dept Radiol, 101 Heukseok Ro, Seoul 06973, South Korea
[8] Seoul Natl Univ Hosp, Dept Internal Med, 101 Daehak Ro, Seoul 03080, South Korea
[9] Seoul Natl Univ, Med Res Ctr, Inst Radiat Med, 103 Daehak Ro, Seoul 03087, South Korea
关键词
pancreas; MRI; intraductal papillary mucinous neoplasm; surveillance; MRCP; PAPILLARY MUCINOUS NEOPLASM; INTERNATIONAL CONSENSUS GUIDELINES; DIFFUSION-WEIGHTED MRI; CLINICAL FEASIBILITY; IMAGE-QUALITY; BREATH-HOLD; MANAGEMENT; CHOLANGIOPANCREATOGRAPHY; MALIGNANCY; ADENOCARCINOMA;
D O I
10.1002/jmri.28189
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Background Pancreatobiliary MRI is often recommended for patients at risk of developing pancreas cancer. But the surveillance MRI protocol has not yet been widely accepted. Purpose To establish an accelerated MRI protocol targeting the table time of 15 minutes for pancreatic cancer surveillance and test its performance in lesion characterization. Study type Prospective. Population A total of 30 participants were enrolled, who were undergoing follow-up care for intraductal papillary mucinous neoplasms or newly diagnosed pancreatic cysts (>= 10 mm) and were scheduled for or had recently undergone contrast-enhanced CT (CECT). Field strength/sequence A 3 T; heavily T2WI, 3D MRCP, DWI, dynamic T1WI, two-point Dixon. Assessment In-room time and table time were measured. Seven radiologists independently reviewed image quality of MRI and then the presence of high-risk stigmata and worrisome features in addition to diagnostic confidence for accelerated MRI, CECT, and the noncontrast part of accelerated MRI (NC-MRI). Statistical analysis Fisher's exact test was used for categorical variables and either the Student's t-test or Mann-Whitney test was performed for continuous variables. The generalized estimated equation was used to compare the diagnostic performance of examinations on a per-patient basis. Interobserver agreement was evaluated via Fleiss kappa. A P value of The in-room time was 18.5 +/- 2.6 minutes (range: 13.7-24.9) and the table time was 13.9 +/- 1.9 minutes (range: 10.7-17.5). There was no significant difference between the diagnostic performances of the three examinations (pooled sensitivity: 75% for accelerated MRI and CECT, 68% for NC-MRI, P = 0.95), with the highest significant diagnostic confidence for accelerated MRI (4.2 +/- 0.1). With accelerated MRI, the interobserver agreement was fair to excellent for high-risk stigmata (kappa = 0.34-0.98). Data Conclusion Accelerated MRI protocol affords a table time of 15 minutes, making it potentially suitable for cancer surveillance in patients at risk of developing pancreatic cancer. Evidence level 2 Technical efficacy stage 2
引用
收藏
页码:1757 / 1768
页数:12
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