Degradable Anti-Biofouling Polyester Coatings with Controllable Lifetimes

被引:1
作者
Mu, Gaoyan [1 ]
Genzer, Jan [2 ]
Gorman, Christopher B. [1 ]
机构
[1] North Carolina State Univ, Dept Chem, Raleigh, NC 27695 USA
[2] North Carolina State Univ, Dept Chem & Biomol Engn, Raleigh, NC 27695 USA
基金
美国国家科学基金会;
关键词
RING-OPENING COPOLYMERIZATION; REACTIVITY RATIOS; PROTEIN ADSORPTION; CYCLIC ANHYDRIDES; EPOXIDES;
D O I
10.1021/acs.langmuir.1c02822
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
To achieve degradable, anti-biofouling coatings with longer lifetimes and better mechanical properties, we synthesized a series of degradable co-polyesters composed of cyclic ketene acetals, di-(ethylene glycol) methyl ether methacrylate, and a photoactive curing agent, 4-benzoylphenyl methacrylate, using a radical ring-opening polymerization. The precursor co-polyesters were spin-coated on a benzophenone-functionalized silicon wafer to form ca. 60 nm films and drop-casted on glass to form similar to 32 mu m films. The copolymers were cross-linked via UV irradiation at 365 nm. The degradation of films was studied by immersing the specimens in aqueous buffers of different pH values. The results show that both the pH of buffer solutions and gel fractions of networks affect the degradation rate. The coatings show good bovine serum albumin resistance capability. By adjusting the fractions of monomers, the degradation rate and degree of hydration (e.g., swelling ratio) are controllable.
引用
收藏
页码:1488 / 1496
页数:9
相关论文
共 31 条
[1]   Biofouling: lessons from nature [J].
Bixler, Gregory D. ;
Bhushan, Bharat .
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES, 2012, 370 (1967) :2381-2417
[2]   Reversible Protein Adsorption on Mixed PEO/PAA Polymer Brushes: Role of Ionic Strength and PEO Content [J].
Bratek-Skicki, Anna ;
Eloy, Pierre ;
Morga, Maria ;
Dupont-Gillain, Christine .
LANGMUIR, 2018, 34 (09) :3037-3048
[3]   Polymer Zwitterions with Phosphonium Cations [J].
Brown, Marcel U. ;
Triozzi, Alexandria ;
Emrick, Todd .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2021, 143 (17) :6528-6532
[4]   Ring-Opening Copolymerization of Maleic Anhydride with Epoxides: A Chain-Growth Approach to Unsaturated Polyesters [J].
DiCiccio, Angela M. ;
Coates, Geoffrey W. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2011, 133 (28) :10724-10727
[5]   Amphiphilic Marine Antifouling Coatings Based on a Hydrophilic Polyvinylpyrrolidone and Hydrophobic Fluorine-Silicon-Containing Block Copolymer [J].
Guo, Hongshuang ;
Chen, Pengguang ;
Tian, Shu ;
Ma, Yiming ;
Li, Qingsi ;
Wen, Chiyu ;
Yang, Jing ;
Zhang, Lei .
LANGMUIR, 2020, 36 (48) :14573-14581
[6]   Radical Ring-Opening Copolymerization of Cyclic Ketene Acetals and Maleimides Affords Homogeneous Incorporation of Degradable Units [J].
Hill, Megan R. ;
Guegain, Elise ;
Tran, Johanna ;
Figg, C. Adrian ;
Turner, Andrew C. ;
Nicolas, Julien ;
Sumerlin, Brent S. .
ACS MACRO LETTERS, 2017, 6 (10) :1071-1077
[7]   Silicone-Based Fouling-Release Coatings for Marine Antifouling [J].
Hu, Peng ;
Xie, Qingyi ;
Ma, Chunfeng ;
Zhang, Guangzhao .
LANGMUIR, 2020, 36 (09) :2170-2183
[8]   Resisting protein adsorption on biodegradable polyester brushes [J].
Hu, Xinfang ;
Gorman, Christopher B. .
ACTA BIOMATERIALIA, 2014, 10 (08) :3497-3504
[9]   Comparison of the Growth and Degradation of Poly(glycolic acid) and Poly(ε-caprolactone) Brushes [J].
Hu, Xinfang ;
Hu, Gongfang ;
Crawford, Kaitlyn ;
Gorman, Christopher B. .
JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2013, 51 (21) :4643-4649
[10]   Quantitative and Qualitative Evaluation of Adsorption/Desorption of Bovine Serum Albumin on Hydrophilic and Hydrophobic Surfaces [J].
Jeyachandran, Y. L. ;
Mielezarski, E. ;
Rai, B. ;
Mielczarski, J. A. .
LANGMUIR, 2009, 25 (19) :11614-11620