Cholesterol and mortality in heart failure: The bad gone good?

被引：11

作者：

Fonarow, GC ^{[1
]}

Horwich, TB ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Div Cardiol, Ahmanson UCLA Cardiomyopathy Ctr, Los Angeles, CA 90095 USA

来源：

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY | 2003年 / 42卷 / 11期

关键词：

D O I：

10.1016/j.jacc.2003.09.005

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Hypercholesterolemia is a well-established risk factor for the development of coronary artery disease (CAD) and for CAD mortality (1). Elevated serum cholesterol levels were also a risk factor for the development of heart failure (HF) in the Framingham study (2). Reduction in serum total cholesterol levels with 3-hydroxy-3-methyl-glutaryl coenzyme A (HMG CoA) reductase inhibitors (statins) in patients with CAD has resulted in a reduction in new-onset HF (3). Because CAD is a dominant etiology of HF, it would be reasonable to expect that high cholesterol would also be a risk factor and have deleterious effects for mortality in patients with established HF.

引用

收藏

页码：1941 / 1943

页数：3

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