Chemistry and radiochemistry of As, Re and Rh isotopes relevant to radiopharmaceutical applications: high specific activity radionuclides for imaging and treatment

被引：17

作者：

Feng, Yutian ^{[1
]}

Phelps, Tim E. ^{[1
]}

Carroll, Valerie ^{[1
]}

Gallazzi, Fabio ^{[2
]}

Sieckman, Gary ^{[3
]}

Hoffman, Timothy J. ^{[3
]}

Barnes, Charles L. ^{[1
]}

Ketring, Alan R. ^{[4
]}

Hennkens, Heather M. ^{[4
]}

Jurisson, Silvia S. ^{[1
]}

机构：

[1] Univ Missouri, Dept Chem, Columbia, MO 65211 USA

[2] Univ Missouri, Struct Biol Core, Columbia, MO 65211 USA

[3] Harry S Truman Mem Vet Hosp, Res Div, Columbia, MO 65201 USA

[4] Univ Missouri, Univ Missouri Res Reactor Ctr MURR, Columbia, MO 65211 USA

来源：

DALTON TRANSACTIONS | 2017年 / 46卷 / 42期

关键词：

IN-VIVO EVALUATION; VITRO/IN VIVO; CHROMATOGRAPHIC-SEPARATION; PROTON-BOMBARDMENT; ARSENIC COMPOUNDS; BOMBESIN ANALOG; TUMOR-BEARING; HIGH-AFFINITY; MOUSE MODEL; COMPLEXES;

D O I：

10.1039/c7dt02407j

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The chemistry and radiochemistry of high specific activity radioisotopes of arsenic, rhenium and rhodium are reviewed with emphasis on University of Missouri activities over the past several decades, and includes recent results. The nuclear facilities at the University of Missouri (10 MW research reactor and 16.5 MeV GE PETtrace cyclotron) allow research and development into novel theranostic radionuclides. The production, separation, enriched target recovery, radiochemistry, and chelation chemistry of As-72,As-77, Re-186,Re-188 and Rh-105 are discussed.

引用

页码：14677 / 14690

页数：14

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