Invasion and dissemination of Yersinia enterocolitica in the mouse infection model

被引:0
作者
Truelzsch, Konrad [1 ]
Oellerich, Mark F. [1 ]
Heesemann, Juergen [1 ]
机构
[1] Univ Munich, Max Von Pettenkofer Inst Hyg & Med Microbiol, Munich, Germany
来源
GENUS YERSINIA: FROM GENOMICS TO FUNCTION | 2007年 / 603卷
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暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Yersinia enterocolitica is one of the most common causes of food borne gastrointestinal disease. After oral uptake yersiniae replicate in the small intestine, invade Peyer's patches of the distal ileum and disseminate to spleen and liver. In these tissues and organs yersiniae replicate extracellularly and form exclusively monoclonal nucroabscesses. Only very few yersiniae invade Peyer's patches and establish just a very few monoclonal microabscesses. This is due to both Yersinia and host specific factors.
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页码:279 / 285
页数:7
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