Biomarkers and Right Ventricular Dysfunction

被引:22
作者
Pradhan, Natasha M. [1 ]
Mullin, Christopher [2 ]
Poor, Hooman D. [1 ]
机构
[1] Mt Sinai Hosp, Icahn Sch Med, Div Pulm Crit Care & Sleep Med, 1 Gustave L Levy Pl, New York, NY 10029 USA
[2] Brown Univ, Warren Alpert Med Sch, Div Pulm Crit Care & Sleep Med, 593 Eddy St, Providence, RI 02903 USA
关键词
Right ventricular dysfunction; Biomarkers; Pulmonary embolism; Pulmonary hypertension; Troponin; Brain natriuretic peptide; BRAIN NATRIURETIC PEPTIDE; ACUTE PULMONARY-EMBOLISM; CARDIAC TROPONIN-T; GELATINASE-ASSOCIATED LIPOCALIN; CORONARY-HEART-DISEASE; ACID-BINDING PROTEIN; ACUTE KIDNEY INJURY; RISK STRATIFICATION; EUROPEAN-SOCIETY; PROTECTIVE VENTILATION;
D O I
10.1016/j.ccc.2019.08.011
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Right ventricular failure is common in critically ill patients, as it frequently results from pulmonary embolism or pulmonary hypertension, and can complicate sepsis and the acute respiratory distress syndrome. Right ventricular dysfunction can be challenging to manage and is associated with poor outcomes in this wide array of disease. Laboratory biomarkers are rapid, noninvasive, accurate, and widely available and thus are useful in the diagnosis and management of right ventricular dysfunction in the critically ill patient. This article discusses the pathophysiology of right ventricular failure and reviews the applications of commonly used biomarkers in right ventricular dysfunction in critical care.
引用
收藏
页码:141 / +
页数:14
相关论文
共 82 条
[1]  
ADGEY AAJ, 1968, LANCET, V2, P1097
[2]   Prognostic Significance of Biomarkers in Pulmonary Arterial Hypertension [J].
Al-Naamani, Nadine ;
Palevsky, Harold I. ;
Lederer, David J. ;
Horn, Evelyn M. ;
Mathai, Stephen C. ;
Roberts, Kari E. ;
Tracy, Russell P. ;
Hassoun, Paul M. ;
Girgis, Reda E. ;
Shimbo, Daichi ;
Post, Wendy S. ;
Kawut, Steven M. .
ANNALS OF THE AMERICAN THORACIC SOCIETY, 2016, 13 (01) :25-30
[3]   Myocardial infarction redefined -: A consensus Document of the Joint European Society of Cardiology/American College of Cardiology Committee for the Redefinition of Myocardial Infarction [J].
Alpert, JS ;
Antman, E ;
Apple, F ;
Armstrong, PW ;
Bassand, JP ;
de Luna, AB ;
Beller, G ;
Breithardt, G ;
Chaitman, BR ;
Clemmensen, P ;
Falk, E ;
Fishbein, MC ;
Galvani, M ;
Garson, A ;
Grines, C ;
Hamm, C ;
Jaffe, A ;
Katus, H ;
Kjekshus, J ;
Klein, W ;
Klootwijk, P ;
Lenfant, C ;
Levy, D ;
Levy, RI ;
Luepker, R ;
Marcus, F ;
Näslund, U ;
Ohman, M ;
Pahlm, O ;
Poole-Wilson, P ;
Popp, R ;
Alto, P ;
Pyörälä, K ;
Ravkilde, J ;
Rehnquist, N ;
Roberts, W ;
Roberts, R ;
Roelandt, J ;
Rydén, L ;
Sans, S ;
Simoons, ML ;
Thygesen, K ;
Tunstall-Pedoe, H ;
Underwood, R ;
Uretsky, BF ;
Van de Werf, F ;
Voipio-Pulkki, LM ;
Wagner, G ;
Wallentin, L ;
Wijns, W .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2000, 36 (03) :959-969
[4]   RIGHT VENTRICULAR INFARCTION - FREQUENCY, SIZE AND TOPOGRAPHY IN CORONARY HEART-DISEASE - A PROSPECTIVE-STUDY COMPRISING 107 CONSECUTIVE AUTOPSIES FROM A CORONARY-CARE UNIT [J].
ANDERSEN, HR ;
FALK, E ;
NIELSEN, D .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1987, 10 (06) :1223-1232
[5]   Prognostic Value of Biomarkers in Acute Non-massive Pulmonary Embolism: A Systematic Review and Meta-analysis [J].
Bajaj, Anurag ;
Rathor, Parul ;
Sehgal, Vishal ;
Kabak, Besher ;
Shetty, Ajay ;
Al Masalmeh, Ossama ;
Hosur, Srikanth .
LUNG, 2015, 193 (05) :639-651
[6]   Prognostic value of troponins in acute pulmonary embolism - A meta-analysis [J].
Becattini, Cecilia ;
Vedovati, Maria Cristina ;
Agnelli, Giancarlo .
CIRCULATION, 2007, 116 (04) :427-433
[7]   Acute pulmonary embolism: mortality prediction by the 2014 European Society of Cardiology risk stratification model [J].
Becattini, Cecilia ;
Agnelli, Giancarlo ;
Lankeit, Mareike ;
Masotti, Luca ;
Pruszczyk, Piotr ;
Casazza, Franco ;
Vanni, Simone ;
Nitti, Cinzia ;
Kamphuisen, Pieter ;
Vedovati, Maria Cristina ;
De Natale, Maria Grazia ;
Konstantinides, Stavros .
EUROPEAN RESPIRATORY JOURNAL, 2016, 48 (03) :780-786
[8]   Venous Thromboembolism A Public Health Concern [J].
Beckman, Michele G. ;
Hooper, W. Craig ;
Critchley, Sara E. ;
Ortel, Thomas L. .
AMERICAN JOURNAL OF PREVENTIVE MEDICINE, 2010, 38 (04) :S495-S501
[9]   Predicting Survival in Pulmonary Arterial Hypertension Insights From the Registry to Evaluate Early and Long-Term Pulmonary Arterial Hypertension Disease Management (REVEAL) [J].
Benza, Raymond L. ;
Miller, Dave P. ;
Gomberg-Maitland, Mardi ;
Frantz, Robert P. ;
Foreman, Aimee J. ;
Coffey, Christopher S. ;
Frost, Adaani ;
Barst, Robyn J. ;
Badesch, David B. ;
Elliott, C. Gregory ;
Liou, Theodore G. ;
McGoon, Michael D. .
CIRCULATION, 2010, 122 (02) :164-U138
[10]   Prevalence and prognosis of cor pulmonale during protective ventilation for acute respiratory distress syndrome [J].
Boissier, Florence ;
Katsahian, Sandrine ;
Razazi, Keyvan ;
Thille, Arnaud W. ;
Roche-Campo, Ferran ;
Leon, Rusel ;
Vivier, Emmanuel ;
Brochard, Laurent ;
Vieillard-Baron, Antoine ;
Brun-Buisson, Christian ;
Dessap, Armand Mekontso .
INTENSIVE CARE MEDICINE, 2013, 39 (10) :1725-1733