The Laminin Binding Integrin α6β1 in Prostate Cancer Perineural Invasion

被引：59
作者：
Sroka, Isis C. [1 ,2 ]
Anderson, Todd A. [1 ]
McDaniel, Kathy M. [1 ]
Nagle, Raymond B. [1 ,3 ]
Gretzer, Matthew B. [1 ,4 ]
Cress, Anne E. [1 ,5 ]
机构：
[1] Univ Arizona, Arizona Canc Ctr, Tucson, AZ 85724 USA
[2] Univ Arizona, Dept Pharmacol, Tucson, AZ 85724 USA
[3] Univ Arizona, Dept Pathol, Tucson, AZ 85724 USA
[4] Univ Arizona, Dept Surg, Tucson, AZ 85724 USA
[5] Univ Arizona, Dept Cell Biol & Anat, Tucson, AZ 85724 USA
来源：
JOURNAL OF CELLULAR PHYSIOLOGY | 2010年 / 224卷 / 02期
关键词：
EXTRACELLULAR-MATRIX PROTEINS; DIFFERENTIAL EXPRESSION; SCHWANN-CELLS; PLASMINOGEN-ACTIVATOR; EPIDERMOLYSIS-BULLOSA; PANCREATIC-CANCER; GENE-EXPRESSION; NEEDLE-BIOPSY; CLEAVAGE; RECEPTOR;
D O I：
10.1002/jcp.22149
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Metastasizing prostate tumor cells invade along nerves innervating the encapsulated human prostate gland in a process known as perineural invasion. The extacellular matrix laminin class of proteins line the neural route and tumor cells escaping from the gland express the laminin binding integrin alpha beta 1 as a prominent cell surface receptor. Integrin alpha 6 beta 1 promotes aggressive disease and supports prostate tumor cell metastasis to bone. Laminins and their integrin receptors are necessary for the development and maintenance of the peripheral nervous system, indicating the potential role for integrin receptors in directing prostate tumor cell invasion on nerves during perineural invasion. J. Cell. Physiol. 224: 283-288, 2010. (C) 2010 Wiley-Liss, Inc.
引用
收藏
页码：283 / 288
页数：6
相关论文
共 80 条
[1]   Bystin in perineural invasion of prostate cancer [J].
Ayala, GE ;
Dai, H ;
Li, RL ;
Ittmann, M ;
Thompson, TC ;
Rowley, D ;
Wheeler, TM .
PROSTATE, 2006, 66 (03) :266-272
[2]   Growth and survival mechanisms associated with perineural invasion in prostate cancer [J].
Ayala, GE ;
Dai, H ;
Ittmann, M ;
Li, R ;
Powell, M ;
Frolov, A ;
Wheeler, TM ;
Thompson, TC ;
Rowley, D .
CANCER RESEARCH, 2004, 64 (17) :6082-6090
[3]   In vitro dorsal root ganglia and human prostate cell line interaction: Redefining perineural invasion in prostate cancer [J].
Ayala, GE ;
Wheeler, TM ;
Shine, HD ;
Schmelz, M ;
Frolov, A ;
Chakraborty, S ;
Rowley, D .
PROSTATE, 2001, 49 (03) :213-223
[4]   Cancer-Related Axonogenesis and Neurogenesis in Prostate Cancer [J].
Ayala, Gustavo E. ;
Dai, Hong ;
Powell, Michael ;
Li, Rile ;
Ding, Yi ;
Wheeler, Thomas M. ;
Shine, David ;
Kadmon, Dov ;
Thompson, Timothy ;
Miles, Brian J. ;
Ittmann, Michael M. ;
Rowley, David .
CLINICAL CANCER RESEARCH, 2008, 14 (23) :7593-7603
[5]   Membrane type 1 matrix metalloprotease cleaves laminin-10 and promotes prostate cancer cell migration [J].
Bair, EL ;
Chen, ML ;
McDaniel, K ;
Sekiguchi, K ;
Cress, AE ;
Nagle, RB ;
Bowden, GT .
NEOPLASIA, 2005, 7 (04) :380-389
[6]   DIFFERENTIAL EXPRESSION OF ALPHA-6 AND ALPHA-2 VERY LATE ANTIGEN INTEGRINS IN THE NORMAL, HYPERPLASTIC, AND NEOPLASTIC PROSTATE - SIMULTANEOUS DEMONSTRATION OF CELL-SURFACE RECEPTORS AND THEIR EXTRACELLULAR LIGANDS [J].
BONKHOFF, H ;
STEIN, U ;
REMBERGER, K .
HUMAN PATHOLOGY, 1993, 24 (03) :243-248
[7]   Prospective evaluation of lateral biopsies of the peripheral zone for prostate cancer detection [J].
Chang, JJ ;
Shinohara, K ;
Bhargava, V ;
Presti, JC .
JOURNAL OF UROLOGY, 1998, 160 (06) :2111-2114
[8]   Inhibition of CD146 gene expression via RNA interference reduces in vitro perineural invasion on ACC-M cell [J].
Chen, W. ;
Zhang, H. L. ;
Jiang, Y. G. ;
Li, J. H. ;
Liu, B. L. ;
Sun, M. Y. .
JOURNAL OF ORAL PATHOLOGY & MEDICINE, 2009, 38 (02) :198-205
[9]   Laminin γ1 is critical for Schwann cell differentiation, axon myelination, and regeneration in the peripheral nerve [J].
Chen, ZL ;
Strickland, S .
JOURNAL OF CELL BIOLOGY, 2003, 163 (04) :889-899
[10]   Regulation of Schwann Cell Function by the Extracellular Matrix [J].
Chernousov, Michael A. ;
Yu, Wei-Ming ;
Chen, Zu-Lin ;
Carey, David J. ;
Strickland, Sidney .
GLIA, 2008, 56 (14) :1498-1507
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