Intramolecular Aryl-Aryl Coupling of Fluoroarenes through Al2O3-Mediated HF Elimination

被引：47
作者：
Amsharov, K. Yu. [1 ]
Merz, P. [1 ]
机构：
[1] Max Planck Inst Solid State Res, Heisenbergstr 1, D-70569 Stuttgart, Germany
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2012年 / 77卷 / 12期
关键词：
CHEMICAL-SYNTHESIS; END-CAP; CARBON; FULLERENES; ACTIVATION; PRECURSOR;
D O I：
10.1021/jo300783y
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A strategy for effective intramolecular aryl-aryl coupling of fluoroarenes through Al2O3-mediated HF elimination is reported. It is demonstrated that the C-F bond, which is widely believed to be the most passive functionality in organic chemistry, can be reconsidered as a useful functional group allowing very effective C-C bond formation. The solid-state strategy presented in this study opens the possibility for facile syntheses of insoluble extended polycyclic aromatic hydrocarbons.
引用
收藏
页码：5445 / 5448
页数：4
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