Leprosy is still a largely worldwide spread disease but rarely encountered in metropolitan France. Its identification implies a multidisciplinary clinical, pathological and bacteriological diagnosis which is necessary to an efficient antibiotic treatment against a crippling disease which remains curable. Here we report the case of a 24-year-old man who was showing an original both cutaneous and pulmonary presence of acido-alcooloresistant bacillus which have been identified as Mycobacterium leprae by polymerase chain reaction (PCR). This unusual presentation of a cutaneous and pulmonary leprosy raises the problem of its differential diagnoses, including those of non-tuberculosis nnycobacterial infections. (C) 2012 Elsevier Masson SAS. All rights reserved.
机构:
UCL Inst Child Hlth, Genet & Genom Med Programme, London WC1N 1EH, England
Great Ormond St Hosp Children NHS Fdn Trust, North East Thames Reg Genet Serv, London, EnglandSheffield Childrens Hosp NHS Fdn Trust, Sheffield Clin Genet Serv, Sheffield S10 2TH, S Yorkshire, England
机构:
UCL Inst Child Hlth, Genet & Genom Med Programme, London, England
Great Ormond St Hosp Children NHS Fdn Trust, North East Thames Reg Genet Serv, London, EnglandSheffield Childrens Hosp NHS Fdn Trust, Sheffield Clin Genet Serv, Sheffield S10 2TH, S Yorkshire, England