Bacteriophages and their implications on future biotechnology: a review

被引:184
|
作者
Haq, Irshad Ul [1 ]
Chaudhry, Waqas Nasir [1 ]
Akhtar, Maha Nadeem [1 ]
Andleeb, Saadia [1 ]
Qadri, Ishtiaq [1 ]
机构
[1] NUST, NUST Ctr Virol & Immunol NCVI, Islamabad 44000, Pakistan
关键词
Bacteriophage; Phage therapy; Antibiotics; Vaccine; Biocontrol; RANDOM-PEPTIDE LIBRARIES; PHAGE DISPLAY; LISTERIA-MONOCYTOGENES; CELL-BINDING; GENE-TRANSFER; THERAPY; VACCINES; VECTORS; ANTIGEN; LAMBDA;
D O I
10.1186/1743-422X-9-9
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Recently it has been recognized that bacteriophages, the natural predators of bacteria can be used efficiently in modern biotechnology. They have been proposed as alternatives to antibiotics for many antibiotic resistant bacterial strains. Phages can be used as biocontrol agents in agriculture and petroleum industry. Moreover phages are used as vehicles for vaccines both DNA and protein, for the detection of pathogenic bacterial strain, as display system for many proteins and antibodies. Bacteriophages are diverse group of viruses which are easily manipulated and therefore they have potential uses in biotechnology, research, and therapeutics. The aim of this review article is to enable the wide range of researchers, scientists, and biotechnologist who are putting phages into practice, to accelerate the progress and development in the field of biotechnology.
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页数:8
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