A simple overview of toxicity of ionic liquids and designs of biocompatible ionic liquids

被引:51
作者
Kuroda, Kosuke [1 ,2 ]
机构
[1] Kanazawa Univ, Grad Sch Nat Sci & Technol, Fac Biol Sci & Technol, Kakuma Machi, Kanazawa, Ishikawa 9201192, Japan
[2] Kanazawa Univ, Nanomat Res Inst, Kakuma Machi, Kanazawa, Ishikawa 9201192, Japan
基金
日本学术振兴会; 日本科学技术振兴机构;
关键词
MALE F344 RATS; CYTOCHROME-C; AQUEOUS-SOLUTION; MOLTEN-SALTS; PRETREATMENT; CELLULOSE; IMIDAZOLIUM; SOLVENTS; BIOMASS; CYTOTOXICITY;
D O I
10.1039/d2nj02634a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Evaluation of toxicity of ionic liquids has been less prioritized, compared to the development of new ionic liquids and their applications. Focus on the toxicity of ionic liquids should be enhanced, since ionic liquids have been intensively industrialized for decades. Their toxicity is related to not only biological applications but also others, since accidents, such as leakage, can occur at any time. This current review aims at systematically summarizing the general trend between the chemical structure and toxicity of ionic liquids across biological species. It also provides a perspective on the current strategies for the development of low-toxicity ionic liquids and their applications.
引用
收藏
页码:20047 / 20052
页数:7
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