One-pot self-assembly of mesoporous silica nanoparticle-based pH-responsive anti-cancer nano drug delivery system

被引：35

作者：

He, Qianjun ^{[1
]}

Gao, Yu ^{[2
]}

Zhang, Lingxia ^{[1
]}

Bu, Wenbo ^{[1
]}

Chen, Hangrong ^{[1
]}

Li, Yaping ^{[2
]}

Shi, Jianlin ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China

来源：

JOURNAL OF MATERIALS CHEMISTRY | 2011年 / 21卷 / 39期

关键词：

SIZE; GLYCOPROTEIN; RELEASE; POLYMER; CELLS;

D O I：

10.1039/c1jm13598h

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A mesoporous silica nanoparticle (MSN)-based pH-responsive nano drug delivery system (hydrophobic drugs@micelles@MSNs) is constructed by a one-pot self-assembly strategy, exhibiting improved drug efficacy against both drug-resistant and drug-sensitive cancer cells.

引用

页码：15190 / 15192

页数：3

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