One Pot Synthesis and Antibacterial Activity of 3,5-Dibromo-2,4-dihydroxy Substituted Chalcones

被引：0
|
作者：
Devpura, Anju [1 ]
Sharma, Parul [1 ]
Chundawat, Sumer Singh [1 ]
Shaktawat, Sheetal [1 ]
Dulawat, Shiv S. [1 ]
机构：
[1] BN Post Grad Coll, Dept Chem, Udaipur 313001, India
来源：
ASIAN JOURNAL OF CHEMISTRY | 2011年 / 23卷 / 10期
关键词：
Microwave; Solid-phase synthesis; Chalcone; Antibacterial activity; MICROWAVE; PYRIMIDINES;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
In an effort to develop antibacterial agents, a series of chalcones were prepared by Claisen-Schmidt condensation of appropriate acetophenones with appropriate aromatic aldehydes in the presence of basic alumina as solid support reagent under microwave irradiation. The synthesized compounds were characterized by their IR, (1)H NMR, mass spectral data and elemental analysis. The compounds have been screened for their antibacterial activity against S. aureus, S. fecalis, E. coli and P mirbilis.
引用
收藏
页码：4649 / 4651
页数：3
相关论文
共 50 条
  • [21] ONE-POT SYNTHESIS OF 3,5-DIPHENYL-1H-PYRAZOLES FROM CHALCONES AND HYDRAZINE UNDER MECHANOCHEMICAL BALL MILLING
    Zhang, Ze
    Tan, Ya-Jun
    Wang, Chun-Shan
    Wu, Hao-Hao
    HETEROCYCLES, 2014, 89 (01) : 103 - 112
  • [22] Oxidation of dimedone by hydrobromic acid in dimethyl sulfoxide and the synthesis of 3,5-dibromo-2,6-dihydroxy-4,4-dimethyl-2,5-cyclohexadien-1-one and 3,5,5-tribromo-4,4-dimethyl-2-hydroxy-2-cyclopenten-1-one
    Yusubov, MS
    Zholobova, GA
    Khabikher, V
    Filimonov, VD
    ZHURNAL ORGANICHESKOI KHIMII, 1997, 33 (02): : 184 - 187
  • [23] Microwave Assisted Eco-friendly Synthesis of Chalcones using 2,4-dihydroxy Acetophenone and Aldehydes as Corrosion Inhibitors for Mild Steel in 1M HCl
    Verma, Chandra Bhan
    Reddy, Mareddy Jayanth
    Quraishi, Mumtaz Ahmad
    ANALYTICAL & BIOANALYTICAL ELECTROCHEMISTRY, 2014, 6 (03): : 321 - 340
  • [24] CERIUM (IV) INDUCED ONE POT SYNTHESIS OF 2,4-DIHYDROXY-3-NITRO ACETOPHENONE - A MODEL FOR BIOMIMETIC AROMATIC HYDROXYLATIONS
    CHAWLA, HM
    MITTAL, RS
    CURRENT SCIENCE, 1983, 52 (24): : 1189 - 1190
  • [25] Synthesis of 3,5-dihydroxy-2,4-dimethylheptanoic acid δ-lactone in enantiomerically pure form
    Chakraborty, TK
    Tapadar, S
    Roy, S
    ARKIVOC, 2005, : 170 - 178
  • [26] A facile one-pot microwave assisted conversion of 3′-5′-dibromo/diiodo-4′-hydroxy substituted chalcones to 2-substituted-4,6-diaryl pyrimidines using S-benzylisothiouronium chloride (SBT) and their antibacterial activities
    Gahlot, US
    Rao, SS
    Dulawat, SS
    Ameta, KL
    Verma, BL
    AFINIDAD, 2003, 60 (508) : 558 - 562
  • [27] Synthesis and antibacterial activity of 4-arylazo-1-substituted-3,5-diphenylpyrazoles
    Amir, M
    Khan, SA
    Drabu, S
    JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 2002, 79 (03) : 280 - 281
  • [28] One-pot Synthesis of 2,4-Diamino-substituted Thieno[3,2-d]pyrimidines
    Li Xiaoying
    Zhang Yangming
    Tang Jie
    Yang Fan
    Nan Fajun
    CHINESE JOURNAL OF CHEMISTRY, 2010, 28 (08) : 1437 - 1440
  • [29] Synthesis, Anticancer, and Antibacterial Studies of Benzylidene Bearing 5-substituted and 3,5-disubstituted-2,4-Thiazolidinedione Derivatives
    Sethi, Navjot Singh
    Prasad, Deo Nandan
    Singh, Rajesh K.
    MEDICINAL CHEMISTRY, 2021, 17 (04) : 369 - 379
  • [30] Synthesis, Antibacterial Activity, and Molecular Docking Study of Chalcones Containing a Thiazolidine-2,4-dione Moiety
    Shyamsunder, M.
    Sudhakar, Ch.
    Sahoo, B. K.
    RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2024, 60 (06) : 1136 - 1144
12345