Presence of Borrelia burgdorferi "Sensu Lato" in patients with morphea from the Amazonic region in Brazil

被引:8
作者
Santos, Monica [1 ,2 ]
Ribeiro-Rodrigues, Rodrigo [3 ]
Talhari, Carolina [1 ,2 ]
Ferreira, Luiz C. L. [1 ,4 ]
Zelger, Bernhard [5 ]
Talhari, Sinesio [1 ]
机构
[1] Fundacao Med Trop Amazonas, Dept Dermatol, Amazonas, Brazil
[2] Amazonas State Univ, Manaus, Amazonas, Brazil
[3] Univ Fed Espirito Santo, Cellular & Mol Immunol Lab, Nucleo Doencas Infecciosas & Pathol Dept, Vitoria, Brazil
[4] Fundacao Med Trop Amazonas, Div Pathol, Amazonas, Brazil
[5] Innsbruck Med Univ, Dept Dermatol & Venerol, Innsbruck, Austria
关键词
SCLEROSUS-ET-ATROPHICUS; FOCUS FLOATING MICROSCOPY; POLYMERASE-CHAIN-REACTION; LICHEN-SCLEROSUS; LOCALIZED SCLERODERMA; CUTANEOUS BORRELIOSIS; ANTIBODY REACTIVITY; STRICTO ANTIGENS; LYME-DISEASE; INFECTION;
D O I
10.1111/j.1365-4632.2011.05081.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Background In the present study, Borrelia spirochetes were found in four (26,6%) out of 15 patients with Atrophoderma of Pasini and Pierini (IAPP) and lichen sclerosis et atrophicans (LSA) from the Brazilian Amazon Region. Material and methods Borreliosis was investigated by immunohistochemistry and focus floating microscopy for Borrelia burgdorferi in skin biopsy samples from 15 patients with both clinical and histopathology evidences compatible with Morphea, LSA, and IAPP. Results Spirochetes were detected by specific immunohistochemistry and focus floating microscopy for B. burgdorferi in samples from three patients. A limitation of our study was the fact that we were not able to isolate and culture these organisms. Conclusion Our data confirm the presence of borreliosis cases in the Amazon.
引用
收藏
页码:1373 / 1378
页数:6
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