Beam-shifting technique for speckle reduction and flow rate measurement in optical coherence tomography

被引：11
作者：
Chen, Chaoliang [1 ]
Shi, Weisong [1 ,2 ]
Deorajh, Ryan [1 ]
Nguyen, Nhu [1 ]
Ramjist, Joel [1 ]
Marques, Andrew [1 ]
Yang, Victor X. D. [1 ,3 ,4 ]
机构：
[1] Ryerson Univ, Dept Elect & Comp Engn, Biophoton & Bioengn Lab, Toronto, ON M5B 2K3, Canada
[2] Nanjing Univ Sci & Technol, Dept Opt Engn, Nanjing 210094, Jiangsu, Peoples R China
[3] Sunnybrook Hlth Sci Ctr, Div Neurosurg, Toronto, ON M4N 3M5, Canada
[4] Univ Toronto, Div Neurosurg, Fac Med, Toronto, ON M5S 3H7, Canada
来源：
OPTICS LETTERS | 2018年 / 43卷 / 24期
基金：
加拿大自然科学与工程研究理事会;
关键词：
VELOCITY; IMAGES; SPEED;
D O I：
10.1364/OL.43.005921
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
In this Letter, we propose a beam-shifting optical coherence tomography scheme for speckle reduction and blood flow rate calculation, where variations of the speckle pattern and Doppler angle were generated by parallel shifting of the sample beam incident on the objective lens. The resultant optical coherent tomography images could then be averaged for speckle noise reduction and simultaneously analyzed for flow rate measurement. The performance of the proposed technique was verified by both phantom and in vivo experiments. (c) 2018 Optical Society of America
引用
收藏
页码：5921 / 5924
页数：4
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