RECURRENT ATRIAL FIBRILLATION IN A PATIENT WITH ULCERATIVE COLITIS TREATED WITH AZATHIOPRINE: CASE REPORT AND REVIEW OF THE LITERATURE

被引：14

作者：

Riccioni, G. ^{[1
]}

Bucciarelli, V. ^{[2
]}

Di Ilio, E. ^{[2
]}

Scotti, L. ^{[2
]}

Aceto, A. ^{[2
]}

D'Orazio, N. ^{[2
]}

Martini, F. ^{[2
]}

Bucciarelli, T. ^{[2
]}

机构：

[1] San Camillo De Lellis Hosp, Cardiol Unit, Foggia, Italy

[2] Univ G DAnnunzio, Dept Biomed Sci, Chieti, Italy

来源：

INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY | 2011年 / 24卷 / 01期

关键词：

azathioprine; ulcerative colitis; atrial fibrillation;

D O I：

10.1177/039463201102400131

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We present a clinical case report regarding recurrent atrial fibrillation in a patient with ulcerative colitis treated with azathioprine. Atrial fibrillation represents the most common sustained cardiac arrhythmia, occurring in 1-2% of the general population and characterized by seemingly disorganized atrial depolarizations without effective atrial contraction. Several mechanisms determine this arrhythmia; in particular remodelling (structural, mechanical and electrical alteration related to atrial fibrillation). The pro-arrhythmic effect of azathioprine may be evaluated during immunosuppressive therapy to be aware of this serious but reversible adverse effect.

引用

页码：247 / 249

页数：3

共 7 条

[1]

[Anonymous], 2010, Arq. Gastroenterol., V47, P313, DOI 10.1590/S0004-28032010000300019

[2]

Allessie MA, 2001, CIRCULATION, V103, P769

[3] New onset of atrial fibrillation after introduction of azathioprine in ulcerative colitis: case report and review of the literature [J].

Cassinotti, Andrea ;

Massari, Alessandro ;

Ferrara, Elisa ;

Greco, Salvatore ;

Bosani, Matteo ;

Ardizzone, Sandro ;

Porro, Gabriele Bianchi .

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2007, 63 (09) :875-878

[4]

MURPHY G, 1985, BRIT MED J, V291, P1049, DOI 10.1136/bmj.291.6501.1049-a

[5] Population prevalence, incidence, and predictors of atrial fibrillation in the Renfrew/Paisley study [J].

Stewart, S ;

Hart, CL ;

Hole, DJ ;

McMurray, JJV .

HEART, 2001, 86 (05) :516-521

[6] Current Strategies for the Treatment of Ulcerative Colitis [J].

Yadav, Praveen K. ;

Liu, Zhanju .

RECENT PATENTS ON INFLAMMATION & ALLERGY DRUG DISCOVERY, 2009, 3 (01) :65-72

[7] Atrial fibrillation - A tachycardia-induced atrial cardiomyopathy [J].

Zipes, DP .

CIRCULATION, 1997, 95 (03) :562-564

← 1 →