Iodine-Catalyzed Versatile Synthesis of 4,6-Diarylpyrimidin-2(1H)-ones (DAPMs) via One-Pot, Multicomponent Reaction

被引：18

作者：

Reddy, M. B. Madhusudana ^{[1
]}

Pasha, M. A. ^{[1
]}

机构：

[1] Bangalore Univ, Dept Studies Chem, Bengaluru 560001, India

来源：

SYNTHETIC COMMUNICATIONS | 2011年 / 41卷 / 13期

关键词：

Aldehyde; 4; 6-diarylpyrimidin-2(1h)-one; iodine; ketone; solvent-free reaction; urea; EFFICIENT SYNTHESIS; BLOCKERS; ACID;

D O I：

10.1080/00397911.2010.493263

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[image omitted] An efficient, solvent-free, one-pot, three-component cyclocondensation reaction between aldehyde, ketone, and urea to give 4,6-diarylpyrimidin-2(1H)-ones (DAPMs) using iodine as catalyst is described. This new protocol provides a simple and environmentally benign route along with the associated advantages of good to excellent yield of the products (90-96%) and short reaction times (5-15min) at 80 degrees C.

引用

页码：1875 / 1880

页数：6

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