Quantification of tumor vascularity with contrast-enhanced sonography - Correlation with magnetic resonance imaging and fluorodeoxyglucose autoradiography in an implanted tumor

被引：18
作者：
Fleischer, AC
Donnelly, EF
Grippo, RJ
Black, AS
Hallahan, DE
机构：
[1] Vanderbilt Univ, Med Ctr, Dept Radiol & Radiol Sci, Nashville, TN 37232 USA
[2] Vanderbilt Univ, Med Ctr, Dept Radiat Oncol, Nashville, TN 37232 USA
[3] Vanderbilt Univ, Med Ctr, Sch Med, Nashville, TN 37232 USA
来源：
JOURNAL OF ULTRASOUND IN MEDICINE | 2004年 / 23卷 / 01期
关键词：
contrast-enhanced sonography; fluorodeoxyglucose autoradiography; magnetic resonance imaging; tumor vascularity;
D O I：
10.7863/jum.2004.23.1.37
中图分类号：
O42 [声学];
学科分类号：
070206 ; 082403 ;
摘要：
Objective. To correlate the quantitated tumor vascularity of implanted murine tumors as depicted by contrast-enhanced sonography with estimates made with magnetic resonance imaging and with estimates of the percentage of viable (metabolically active) tumor as depicted by fluorodeoxyglucose autoradiography Methods. Implanted tumors in 10 mice were imaged with contrast-enhanced sonography, magnetic resonance imaging, and fluorodeoxyglucose autoradiography. Tumor vascularity was estimated with each modality and compared with the percentage of viable tumor. Results. Quantitated estimates of tumor vascularity with contrast-enhanced sonography closely correlated (r = 0.95) with estimates made by magnetic resonance imaging and with the percentage of viable tumor (r = 0.93) as depicted by fluorodeoxyglucose autoradiography. Conclusions. Contrast-enhanced sonography accurately depicts tumor vascularity in these implanted tumors. Tumor vascularity correlated with the amount of metabolically active tumor.
引用
收藏
页码：37 / 41
页数：5
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