Effect of laser-induced photodissociation of oxyhemoglobin on biomedical processes

In the present report we draw attention to the phenomenon of laser-induced photodissociation of oxyhemoglobin in cutaneous blood vessels as an important factor in biostimulating and therapeutic action of low energy laser radiation. Calculations of absorption efficiency of laser radiation both by oxyhemoglobin and carbon monoxide hemoglobin were carried out by a computer simulation using Kubelka-Munk model of tissue. It has been shown that the absorption of the oxyhemoglobin in the visible region corresponding to the Q-band of absorption spectra possesses a relatively high selectivity. nle obtained results are discussed in terms of developing new methods for wound healing, as well as for carbon monoacid poisoning. Some aspects of the laser-induced photodissociation of oxyhemoglobin complexes are discussed in view of its practical use for developing new diagnosic methods. An attractive way to use this phenomenon is monitoring of local concentrations of oxygen by laser light irradiation.