It has recently been argued that the facilitation between associated prime-target pairs observed in automatic semantic priming tasks is due to low-level lexical effects. Any "pure" semantic priming is thought to be the result of strategic effects and does not therefore reflect automatic access to lexical semantic representations (e.g. Shelton & Martin, 1992). Not only are such claims based on a narrow definition of semantic relatedness as category co-membership, but it is argued that the methodology employed by Shelton and Martin and other advocates of the intra-lexical priming hypothesis, who have attempted to dissociate semantic and associative effects by devising non-associated semantic prime-target pairs, is fundamentally flawed. Instead, an experiment is reported in which purely lexical-level primes are compared directly with semantic-level primes for the same target items in a sequential lexical decision task. Both types of prime produce facilitation, but only that from the semantic-level primes is significant. It is argued that, contrary to the intra-lexical priming hypothesis, semantic information is required for automatic semantic priming. If it were not, the lexical-level priming in this experiment would have been greater than the semantic-level priming. As it is, the reverse pattern is reported, providing support for the notion of a semantic contribution to the facilitation observed between associated prime-target pairs.