Tumor-Induced Osteomalacia (TIO): Atypical Presentation

被引：6

作者：

Khaliq, Waseem

Cheripalli, Praveen

Tangella, Krishnarao

机构：

[1] Johns Hopkins Univ, Sch Med, Dept Med, Baltimore, MD 21205 USA

[2] Shands Jacksonville Med Ctr, Jacksonville, FL USA

[3] Univ Illinois, Coll Med, Urbana, IL 61801 USA

来源：

SOUTHERN MEDICAL JOURNAL | 2011年 / 104卷 / 05期

关键词：

phosphaturic mesenchymal tumors (PMT); Tumor Induced Osteomalacia (TIO); PHOSPHATURIC MESENCHYMAL TUMOR; ONCOGENIC OSTEOMALACIA; RICKETS;

D O I：

10.1097/SMJ.0b013e31821427db

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Tumor-induced osteomalacia is a rare acquired condition characterized by phosphaturia, hypophosphatemia and osteomalacia. We report an unusual presentation in a 15-year-old healthy male with a two-week history of cough and chest pain. The chest radiograph showed right middle lobe opacity and chest CT revealed a mass in the extra pleural space. A biopsy showed chondro-myxoidstroma with osteoid formation. Diagnosis was confirmed with the above findings and hypophosphatemia. The patient's symptoms resolved after complete surgical excision of the mass. Tumor-induced osteomalacia, although a rare disorder, can be a diagnostic challenge, especially in patients presenting with atypical symptoms.

引用

页码：348 / 350

页数：3