Tumor-Induced Osteomalacia (TIO): Atypical Presentation

被引:6
作者
Khaliq, Waseem
Cheripalli, Praveen
Tangella, Krishnarao
机构
[1] Johns Hopkins Univ, Sch Med, Dept Med, Baltimore, MD 21205 USA
[2] Shands Jacksonville Med Ctr, Jacksonville, FL USA
[3] Univ Illinois, Coll Med, Urbana, IL 61801 USA
关键词
phosphaturic mesenchymal tumors (PMT); Tumor Induced Osteomalacia (TIO); PHOSPHATURIC MESENCHYMAL TUMOR; ONCOGENIC OSTEOMALACIA; RICKETS;
D O I
10.1097/SMJ.0b013e31821427db
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Tumor-induced osteomalacia is a rare acquired condition characterized by phosphaturia, hypophosphatemia and osteomalacia. We report an unusual presentation in a 15-year-old healthy male with a two-week history of cough and chest pain. The chest radiograph showed right middle lobe opacity and chest CT revealed a mass in the extra pleural space. A biopsy showed chondro-myxoidstroma with osteoid formation. Diagnosis was confirmed with the above findings and hypophosphatemia. The patient's symptoms resolved after complete surgical excision of the mass. Tumor-induced osteomalacia, although a rare disorder, can be a diagnostic challenge, especially in patients presenting with atypical symptoms.
引用
收藏
页码:348 / 350
页数:3
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