Selective Detection of Neurotoxin by Photoluminescent Peptide Nanotubes

被引:32
作者
Kim, Jae Hong [1 ]
Ryu, Jungki [1 ]
Park, Chan Beum [1 ]
机构
[1] Korea Adv Inst Sci & Technol, Dept Mat Sci & Engn, Taejon 305701, South Korea
基金
新加坡国家研究基金会;
关键词
CHEMICAL WARFARE AGENTS; NERVE AGENTS; NANOWIRES; DIPHENYLALANINE; TEMPERATURE; SENSORS; WATER; IONS;
D O I
10.1002/smll.201002107
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Photoluminescent peptide nanotubes undergo a drastic quenching of their emission within a few seconds of exposure to paraoxon, a nitro-functionalized neurotoxin. The photoluminescence quenching occurs due to the interruption of cascaded energy transfer from peptide nanotubes to lanthanide ions. The assay platform provides high selectivity toward paraoxon, among other organophosphates, nitro-group compounds, and common organic chemicals; this capability is attributed to the role of the diphenylalanine nanotubes as a host matrix for lanthanide complexes. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:718 / 722
页数:5
相关论文
共 25 条
[11]  
2-H
[12]   Studies on a surface acoustic wave (SAW) dosimeter sensor for organophosphorous nerve agents [J].
Nieuwenhuizen, MS ;
Harteveld, JLN .
SENSORS AND ACTUATORS B-CHEMICAL, 1997, 40 (2-3) :167-173
[13]   Casting metal nanowires within discrete self-assembled peptide nanotubes [J].
Reches, M ;
Gazit, E .
SCIENCE, 2003, 300 (5619) :625-627
[14]   TERBIUM(III) AND EUROPIUM(III) IONS AS LUMINESCENT PROBES AND STAINS FOR BIOMOLECULAR SYSTEMS [J].
RICHARDSON, FS .
CHEMICAL REVIEWS, 1982, 82 (05) :541-552
[15]   High-Temperature Self-Assembly of Peptides into Vertically Well-Aligned Nanowires by Aniline Vapor [J].
Ryu, Jungki ;
Park, Chan Beum .
ADVANCED MATERIALS, 2008, 20 (19) :3754-+
[16]   Solid-phase growth of nanostructures from amorphous peptide thin film: Effect of water activity and temperature [J].
Ryu, Jungki ;
Park, Chan Beum .
CHEMISTRY OF MATERIALS, 2008, 20 (13) :4284-4290
[17]   High Stability of Self-Assembled Peptide Nanowires Against Thermal, Chemical, and Proteolytic Attacks [J].
Ryu, Jungki ;
Park, Chan Beum .
BIOTECHNOLOGY AND BIOENGINEERING, 2010, 105 (02) :221-230
[18]   Photoluminescent Peptide Nanotubles [J].
Ryu, Jungki ;
Lim, Seong Yoon ;
Park, Chan Beum .
ADVANCED MATERIALS, 2009, 21 (16) :1577-+
[19]   Synthesis of Diphenylalanine/Polyaniline Core/Shell Conducting Nanowires by Peptide Self-Assembly [J].
Ryu, Jungki ;
Park, Chan Beum .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (26) :4820-4823
[20]   Terpyridine-lanthanide complexes respond to fluorophosphate containing nerve gas G-agent surrogates [J].
Shunmugam, Raja ;
Tew, Gregory N. .
CHEMISTRY-A EUROPEAN JOURNAL, 2008, 14 (18) :5409-5412