Selective Detection of Neurotoxin by Photoluminescent Peptide Nanotubes

被引：32

作者：

Kim, Jae Hong ^{[1
]}

Ryu, Jungki ^{[1
]}

Park, Chan Beum ^{[1
]}

机构：

[1] Korea Adv Inst Sci & Technol, Dept Mat Sci & Engn, Taejon 305701, South Korea

来源：

SMALL | 2011年 / 7卷 / 06期

基金：

新加坡国家研究基金会;

关键词：

CHEMICAL WARFARE AGENTS; NERVE AGENTS; NANOWIRES; DIPHENYLALANINE; TEMPERATURE; SENSORS; WATER; IONS;

D O I：

10.1002/smll.201002107

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Photoluminescent peptide nanotubes undergo a drastic quenching of their emission within a few seconds of exposure to paraoxon, a nitro-functionalized neurotoxin. The photoluminescence quenching occurs due to the interruption of cascaded energy transfer from peptide nanotubes to lanthanide ions. The assay platform provides high selectivity toward paraoxon, among other organophosphates, nitro-group compounds, and common organic chemicals; this capability is attributed to the role of the diphenylalanine nanotubes as a host matrix for lanthanide complexes. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：718 / 722

页数：5

共 25 条

[1] Thermal and chemical stability of diphenylalanine peptide nanotubes: Implications for nanotechnological applications [J].

Adler-Abramovich, L ;

Reches, M ;

Sedman, VL ;

Allen, S ;

Tendler, SJB ;

Gazit, E .

LANGMUIR, 2006, 22 (03) :1313-1320

[2] Taking advantage of luminescent lanthanide ions [J].

Bünzli, JCG ;

Piguet, C .

CHEMICAL SOCIETY REVIEWS, 2005, 34 (12) :1048-1077

[3] Fluorescent Sensors for the Detection of Chemical Warfare Agents [J].

Burnworth, Mark ;

Rowan, Stuart J. ;

Weder, Christoph .

CHEMISTRY-A EUROPEAN JOURNAL, 2007, 13 (28) :7828-7836

[4] Phenanthroline-derived ratiometric chemosensor for ureas [J].

Engel, Yoni ;

Dahan, Adi ;

Rozenshine-Kemelmakher, Emily ;

Gozin, Michael .

JOURNAL OF ORGANIC CHEMISTRY, 2007, 72 (07) :2318-2328

[5] The structure of nanotubes formed by diphenylalanine, the core recognition motif of Alzheimer's β-amyloid polypeptide [J].

Goerbitz, Carl Henrik .

CHEMICAL COMMUNICATIONS, 2006, (22) :2332-2334

[6] NERVE AGENTS - A REVIEW [J].

GUNDERSON, CH ;

LEHMANN, CR ;

SIDELL, FR ;

JABBARI, B .

NEUROLOGY, 1992, 42 (05) :946-950

[7] Polymer-based lanthanide luminescent sensor for detection of the hydrolysis product of the nerve agent Soman in water [J].

Jenkins, AL ;

Uy, OM ;

Murray, GM .

ANALYTICAL CHEMISTRY, 1999, 71 (02) :373-378

[8] Fluorescent organometallic sensors for the detection of chemical-warfare-agent mimics [J].

Knapton, Daniel ;

Burnworth, Mark ;

Rowan, Stuart J. ;

Weder, Christoph .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (35) :5825-5829

[9] Bio-inspired fabrication of superhydrophobic surfaces through peptide self-assembly [J].

Lee, Joon Seok ;

Ryu, Jungki ;

Park, Chan Beum .

SOFT MATTER, 2009, 5 (14) :2717-2720

[10]

Magennis SW, 2002, CHEM-EUR J, V8, P5761, DOI 10.1002/1521-3765(20021216)8:24<5761::AID-CHEM5761>3.0.CO

← 1 2 3 →