Multimodal analgesia without parenteral narcotics for total knee arthroplasty

被引:54
作者
Dorr, Lawrence D. [1 ]
Raya, Julio [1 ]
Long, William T. [1 ]
Boutary, Myriam [1 ]
Sirianni, Leigh Ellen [1 ]
机构
[1] NIAMSD, Inglewood, CA 90301 USA
关键词
pain; pain medications; narcotics; total knee arthroplasty; multimodal treatment;
D O I
10.1016/j.arth.2007.10.004
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Use of parenteral narcotics after total knee arthroplasty is considered by most orthopedic surgeons to be the standard of care. This study tested the hypothesis that a multimodal oral pain medication protocol could control pain and minimize complications of parenteral narcotics. Postoperative oral analgesia was augmented with either continuous epidural infusion or continuous femoral infusion using ropivacaine only. Seventy patients had total knee arthroplasty with a protocol that included preemptive oral analgesics, epidural anesthesia, pericapsular analgesic injection, and postoperative analgesia without parenteral opioids. The average daily pain score was less than 4 out of 10, nausea occurred in 15 patients (21 %), emesis in 1 patient (1.4%), and there were no severe complications. This study proved the hypothesis that pain after total knee arthroplasty could be effectively managed without routine use of parenteral opioids.
引用
收藏
页码:502 / 508
页数:7
相关论文
共 31 条
[1]   Efficacy of postoperative epidural analgesia - A meta-analysis [J].
Block, BM ;
Liu, SS ;
Rowlingson, AJ ;
Cowan, AR ;
Cowan, JA ;
Wu, CL .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2003, 290 (18) :2455-2463
[2]   Continuous femoral blocks improve recovery and outcome of patients undergoing total knee arthroplasty [J].
Chelly, JE ;
Greger, J ;
Gebhard, R ;
Coupe, K ;
Clyburn, TA ;
Buckle, R ;
Criswell, A .
JOURNAL OF ARTHROPLASTY, 2001, 16 (04) :436-445
[3]   CENTRAL-NERVOUS-SYSTEM PLASTICITY IN THE TONIC PAIN RESPONSE TO SUBCUTANEOUS FORMALIN INJECTION [J].
CODERRE, TJ ;
VACCARINO, AL ;
MELZACK, R .
BRAIN RESEARCH, 1990, 535 (01) :155-158
[4]   SUBCUTANEOUS FORMALIN-INDUCED ACTIVITY OF DORSAL HORN NEURONS IN THE RAT - DIFFERENTIAL RESPONSE TO AN INTRATHECAL OPIATE ADMINISTERED PRE-FORMALIN OR POST-FORMALIN [J].
DICKENSON, AH ;
SULLIVAN, AF .
PAIN, 1987, 30 (03) :349-360
[5]  
DORR LD, 2006, HIP ARTHROPLASTY MIN, P1
[6]  
Flory DA, 2001, ORTHOPEDICS, V24, P243
[7]   Evaluation of a single-dose, extended-release epidural morphine formulation for pain after knee arthroplasty [J].
Hartrick, CT ;
Martin, G ;
Kantor, G ;
Koncelik, J ;
Manvelian, G .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 2006, 88A (02) :273-281
[8]   Low-molecular-weight heparin: Biochemistry, pharmacology, and concurrent drug precautions [J].
Heit, JA .
REGIONAL ANESTHESIA AND PAIN MEDICINE, 1998, 23 (06) :135-139
[9]   Postoperative cognitive impairment in the elderly - Choice of patient-controlled analgesia opioid [J].
Herrick, IA ;
Ganapathy, S ;
Komar, W ;
Kirkby, J ;
Moote, CA ;
Dobkowski, W ;
Eliasziw, M .
ANAESTHESIA, 1996, 51 (04) :356-360
[10]   Analgesia for total hip and knee arthroplasty: A multimodal pathway featuring peripheral nerve block [J].
Horlocker, TT ;
Kopp, SL ;
Pagnano, MW ;
Hebl, JR .
JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS, 2006, 14 (03) :126-135