Current management and novel agents for malignant melanoma

被引：35

作者：

Lee, Byung

Mukhi, Nikhil

Liu, Delong ^{[1
]}

机构：

[1] New York Med Coll, Div Hematol & Oncol, Valhalla, NY 10595 USA

来源：

JOURNAL OF HEMATOLOGY & ONCOLOGY | 2012年 / 5卷

关键词：

RANDOMIZED PHASE-III; METASTATIC MELANOMA; CANCER-IMMUNOTHERAPY; IMATINIB MESYLATE; ADJUVANT THERAPY; DNA-REPAIR; DACARBAZINE; TRIAL; INTERFERON-ALPHA-2B; INHIBITORS;

D O I：

10.1186/1756-8722-5-3

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Advanced malignant melanoma remains a challenging cancer. Over the past year, there have been 3 agents approved for treatment of melanoma by Food and Drug Administration. These include pegylated interferon alpha2b for stage III melanoma, vemurafenib for unresectable or metastatic melanoma with BRAF V600E mutation, and ipilimumab for treatment of unresectable or metastatic melanoma. This review will also update on the development of novel agents, including tyrosine kinase inhibitors and adoptive cellular therapy.

引用

页数：7

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