Terpenoids from the Stems of Drypetes congestiflora

被引：7

作者：

Chen, Wen-Hao ^{[1
]}

Han, Chang-Ri ^{[1
]}

Hui, Yang ^{[1
]}

Zhang, Da-Shuai ^{[1
]}

Song, Xin-Ming ^{[1
]}

Chen, Guang-Ying ^{[1
]}

Song, Xiao-Ping ^{[1
]}

机构：

[1] Hainnan Normal Univ, Minist Educ, Coll Chem & Chem Engn, Key Lab Trop Med Plant Chem, Haikou 571158, Peoples R China

来源：

HELVETICA CHIMICA ACTA | 2015年 / 98卷 / 05期

基金：

中国国家自然科学基金;

关键词：

Drypetes congestiflora; Sesquiterpenoids; Terpenoids; Cytotoxic activity; ANTIMICROBIAL ACTIVITY; CHEMICAL-CONSTITUENTS; TRITERPENOIDS; ROOTS;

D O I：

10.1002/hlca.201400318

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two new eremophilane-type sesquiterpenoids, 1-hydroxyeremophila-6,9,11-trien-8-one (1), 4-hydroxyeremophila-1,9-diene-3,8-dione (2), and a new friedelane-type triterpenoid, friedelane-3,16-diol (4), along with six known terpenoids, 3 and 5-9, have been isolated from the stems of Drypetes congestiflora. Their structures and relative configurations were elucidated on the basis of detailed spectroscopic analyses and by comparison of their NMR data with those reported in the literature. All of the compounds, 1-9, were isolated for the first time from this species. Compound 3 exhibited moderate cytotoxic activities against the A549 and B16F10 cell lines.

引用

页码：724 / 730

页数：7

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