Synthesis of Florbetapir aza-analogues using chemistry of pyridinium N-aminides

被引:0
作者
Gala, Elena [1 ,2 ]
Recio, Javier [1 ]
Alvarez-Builla, Julio [1 ]
Luisa Izquierdo, M. [1 ]
机构
[1] Univ Alcala, Dept Quim Organ & Quim Inorgan, Campus Cient Tecnol, Alcala De Henares 28805, Madrid, Spain
[2] Univ Rey Juan Carlos, Dept Tecnol Quim & Ambiental, Mostoles 28933, Madrid, Spain
关键词
ALZHEIMERS-DISEASE; BETA; DERIVATIVES; RADIOPHARMACEUTICALS;
D O I
10.24820/ark.5550190.p011.676
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
引用
收藏
页数:28
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  • [1] Evaluation of 64Cu-Based Radiopharmaceuticals that Target Aβ Peptide Aggregates as Diagnostic Tools for Alzheimer's Disease
    Bandara, Nilantha
    Sharma, Anuj K.
    Krieger, Stephanie
    Schultz, Jason W.
    Han, Byung Hee
    Rogers, Buck E.
    Mirica, Liviu M.
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2017, 139 (36) : 12550 - 12558
  • [2] Comprehensive Review on Alzheimer's Disease: Causes and Treatment
    Breijyeh, Zeinab
    Karaman, Rafik
    [J]. MOLECULES, 2020, 25 (24):
  • [3] Chalcone Based Homodimeric PET Agent, 11C-(Chal)2DEA-Me, for Beta Amyloid Imaging: Synthesis and Bioevaluation
    Chauhan, Kanchan
    Tiwari, Anjani K.
    Chadha, Nidhi
    Kaul, Ankur
    Singh, Ajai Kumar
    Datta, Anupama
    [J]. MOLECULAR PHARMACEUTICS, 2018, 15 (04) : 1515 - 1525
  • [4] Alzheimer Disease Pathogenesis: Insights From Molecular and Cellular Biology Studies of Oligomeric Aβ and Tau Species
    Chen, Xu-Qiao
    Mobley, William C.
    [J]. FRONTIERS IN NEUROSCIENCE, 2019, 13
  • [5] Fluorinated Benzofuran Derivatives for PET Imaging of β-Amyloid Plaques in Alzheimer's Disease Brains
    Cheng, Yan
    Ono, Masahiro
    Kimura, Hiroyuki
    Kagawa, Shinya
    Nishii, Ryuichi
    Kawashima, Hidekazu
    Sajio, Hideo
    [J]. ACS MEDICINAL CHEMISTRY LETTERS, 2010, 1 (07): : 321 - 325
  • [6] Radiotracers for Amyloid Imaging in Neurodegenerative Disease: State-of-the-Art and Novel Concepts
    Cistaro, Angelina
    Alongi, Pierpaolo
    Caobelli, Federico
    Cassalia, Laura
    [J]. CURRENT MEDICINAL CHEMISTRY, 2018, 25 (26) : 3131 - 3140
  • [7] Pyridinium N-heteroarylaminides: a brief study of the synthesis and reactivity under solvent-free mechanochemical conditions
    Cordoba, Marta
    Abet, Valentina
    Moron, Maria
    Castillo, Rafael R.
    Burgos, Carolina
    Luisa Izquierdo, M.
    [J]. ARKIVOC, 2011, : 156 - 165
  • [8] Carbon-11 labeled stilbene derivatives from natural products for the imaging of Aβ plaques in the brain
    Cui, Mengchao
    Tang, Ruikun
    Zhang, Jinming
    Zhang, Xiaojun
    Li, Zijing
    Jia, Hongmei
    Liu, Boli
    [J]. RADIOCHIMICA ACTA, 2014, 102 (1-2) : 185 - 192
  • [9] Regioselective Synthesis of 2-Amino-5-(or 3-)arylazo-Substituted Pyridines and Pyrazines from Pyridinium N-Aminides
    Gala, Elena
    Jose Reyes, M.
    Alvarez-Builla, Julio
    Luisa Izquierdo, M.
    [J]. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2016, 2016 (12) : 2145 - 2156
  • [10] Preclinical Evaluation of 18F-RO6958948, 11C-RO6931643, and 11C-RO6924963 as Novel PET Radiotracers for Imaging Tau Aggregates in Alzheimer Disease
    Honer, Michael
    Gobbi, Luca
    Knust, Henner
    Kuwabara, Hiroto
    Muri, Dieter
    Koerner, Matthias
    Valentine, Heather
    Dannals, Robert F.
    Wong, Dean F.
    Borroni, Edilio
    [J]. JOURNAL OF NUCLEAR MEDICINE, 2018, 59 (04) : 675 - 681