Straightforward four-component access to spiroindolines

被引：38

作者：

El Kaim, Laurent ^{[1
]}

Grimaud, Laurence ^{[1
]}

Le Goff, Xavier-Frederic ^{[2
]}

Menes-Arzate, Martha ^{[3
]}

Miranda, Luis D. ^{[4
]}

机构：

[1] Ecole Natl Super Tech Avancees, Ecole Polytech ENSTA CNRS, UMR 7652, Lab Chim & Procedes, F-75015 Paris, France

[2] Ecole Polytech, CNRS, Lab Heteroelements & Coordinat, F-91128 Palaiseau, France

[3] Univ Nacl Autonoma Mexico, Fac Med, Mexico City 04510, DF, Mexico

[4] Univ Nacl Autonoma Mexico, Inst Quim, Mexico City 04510, DF, Mexico

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 28期

关键词：

CATALYZED ALLYLIC ALKYLATION; NATURAL-PRODUCTS; PENICILLIUM-EXPANSUM; RADICAL CYCLIZATION; CARBONYL-COMPOUNDS; OXIDATION; INDOLES; ROUTE; (+)-TABERPSYCHINE; (+)-KOUMINE;

D O I：

10.1039/c1cc12236c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Spiroindolines could be synthesized via a very convenient one-pot procedure combining a Ugi coupling and a new copper-catalyzed oxidative process at a peptidyl position. Due to the nature of the first step, this method offers a straightforward access to complex alkaloids with four points of molecular diversity.

引用

页码：8145 / 8147

页数：3

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