In-vitro screening of antifungal activity of plants in Malaysia

被引：0
|
作者：
Nazmul, M. H. M. [1 ]
Salmah, I [2 ]
Syahid, A. [2 ]
Mahmood, A. A. [2 ]
机构：
[1] Univ Teknol MARA, Fac Med, Dept Microbiol, Shah Alam 40450, Selangor, Malaysia
[2] Univ Malaya, Fac Med, Dept Mol Med, Kuala Lumpur, Malaysia
来源：
BIOMEDICAL RESEARCH-INDIA | 2011年 / 22卷 / 01期
关键词：
In-vitro screening; antifungal activity; Malaysian plants; Solid phase extraction; Piper betel;
D O I：
暂无
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Twelve species of local Malaysian plants and 5 strains of medically important fungi were selected for this study. Antifungal susceptibility test was performed to screen the antifungal activity of these plants against the selected fungi. Piper betel produced the best result in antifungal susceptibility testing and showed to possess antifungal property against 4 out of 5 strains of the fungus. Solid Phase extraction (SPE) technique was applied to Piper betel to achieve initial separation of active antifungal compound in the form of methanol fractions. These fractions were tested for their antifungal property. Piper betel showed the best antifungal activity especially against Trichophyton rubrum.
引用
收藏
页码：28 / 30
页数：3
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