Phosphoinositides and host-pathogen interactions

被引:35
|
作者
Pizarro-Cerda, Javier [1 ,2 ,3 ]
Kuehbacher, Andreas [4 ]
Cossart, Pascale [1 ,2 ,3 ]
机构
[1] Inst Pasteur, Unite Interact Bacteries Cellules, F-75015 Paris, France
[2] INSERM, U604, F-75015 Paris, France
[3] INRA, USC2020, F-75015 Paris, France
[4] Fraunhofer Inst Interfacial Engn & Biotechnol IGB, Dept Mol Biotechnol, D-70569 Stuttgart, Germany
来源
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS | 2015年 / 1851卷 / 06期
基金
欧洲研究理事会;
关键词
Listeria; Salmonella; Shigella; Legionella; Mycobacteria; Yersinia; Cytoskeleton; MYCOBACTERIAL PHAGOSOME MATURATION; LEGIONNAIRES-DISEASE BACTERIUM; LISTERIA-MONOCYTOGENES; LEGIONELLA-PNEUMOPHILA; SALMONELLA-TYPHIMURIUM; PHOSPHATIDYLINOSITOL; 3-PHOSPHATE; SHIGELLA INVASION; SECRETION SYSTEM; EPITHELIAL-CELLS; EFFECTOR PROTEIN;
D O I
10.1016/j.bbalip.2014.09.011
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Phosphoinositides control key cellular processes including vesicular trafficking and actin polymerization. Intracellular bacterial pathogens manipulate phosphoinositide metabolism in order to promote their uptake by target cells and to direct in some cases the biogenesis of their replication compartments. In this chapter, we review the molecular strategies that major pathogens including Listeria, Mycobacterium, Shigella, Salmonella, Legionella and Yersinia use to hijack phosphoinositides during infection. This article is part of a Special Issue entitled Phosphoinositides. (C) 2014 Elsevier B.V. All rights reserved.
引用
收藏
页码:911 / 918
页数:8
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