Adenoviral Infection Presenting as an Isolated Central Nervous System Disease without Detectable Viremia in Two Children after Stem Cell Transplantation

被引：18

作者：

Frange, Pierre ^{[1
]}

de Latour, Regis Peffault ^{[2
]}

Arnaud, Cecile ^{[3
]}

Boddaert, Nathalie ^{[4
]}

Oualha, Mehdi ^{[5
]}

Avettand-Fenoel, Veronique ^{[6
]}

Bernaudin, Francoise ^{[3
]}

Aguilar, Claire ^{[7
]}

Barnerias, Christine ^{[8
]}

Leruez-Ville, Marianne ^{[6
]}

Touzot, Fabien ^{[1
]}

Lortholary, Olivier ^{[7
]}

Fischer, Alain ^{[1
]}

Blanche, Stephane ^{[1
]}

机构：

[1] Hop Necker Enfants Malad, APHP, Unite Immunol Hematol & Rhumatol Pediat, F-75015 Paris, France

[2] Hop St Louis, APHP, Serv Hematol Greffe, Paris, France

[3] Ctr Hosp Intercommunal, Ctr Reference Drepanocytose, Serv Pediat, Creteil, France

[4] Hop Necker Enfants Malad, APHP, Serv Radiol Pediat, F-75015 Paris, France

[5] Hop Necker Enfants Malad, APHP, Serv Reanimat Polyvalente Pediat, F-75015 Paris, France

[6] Hop Necker Enfants Malad, APHP, Virol Lab, F-75015 Paris, France

[7] Univ Paris 05, Hop Necker Enfants Malad, APHP, Serv Malad Infect & Trop, F-75015 Paris, France

[8] Hop Necker Enfants Malad, APHP, Serv Neurol Pediat, F-75015 Paris, France

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2011年 / 49卷 / 06期

关键词：

BONE-MARROW-TRANSPLANTATION; RECIPIENTS; DIAGNOSIS; PATHOGEN; BLOOD;

D O I：

10.1128/JCM.00080-11

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We report two cases of adenoviral meningoencephalitis in children following allogeneic stem cell transplantation. These cases showed four similarities: isolated neurological involvement, infiltrating hyperintensities next to the third ventricle on the cerebral magnetic resonance image, the absence of concomitant detectable adenoviral viremia, and a severe clinical outcome.

引用

页码：2361 / 2364

页数：4

共 22 条

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