alpha-Azidoesters as divergent intermediates for combinatorial generation of glucofuranose libraries of novel N-linked glycopeptides

被引：22
作者：
Brandstetter, TW
delaFuente, C
Kim, YH
Cooper, RI
Watkin, DJ
Oikonomakos, NG
Johnson, LN
Fleet, GWJ
机构：
[1] OXFORD CTR MOL SCI,DYSON PERRINS LAB,OXFORD OX1 3QY,ENGLAND
[2] UNIV OXFORD,CHEM CRYSTALLOG LAB,OXFORD OX1 3PD,ENGLAND
[3] NATL HELLEN RES FDN,ATHENS 11635,GREECE
[4] LAB MOL BIOPHYS,OXFORD OX1 3QU,ENGLAND
来源：
TETRAHEDRON | 1996年 / 52卷 / 32期
关键词：
D O I：
10.1016/0040-4020(96)00594-7
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Epimeric azidoesters containing a glucofuranosyl moiety are readily prepared from glucoheptonolactone and may be reduced to corresponding aminoesters; such compounds may be useful intermediates for the generation of combinatorial libraries of glucofuranose mimics and of spiroderivatives of glucofuranose at the anomeric position. The X-ray crystal structure of methyl 2-amino-2-deoxy-3,4-di-O-tert-butyldimethylsilyl-6,7-O-isopropylidene-beta-D-gluco-2-heptulofuranoate is reported. Copyright (C) 1996 Elsevier Science Ltd
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页码：10711 / 10720
页数：10
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