A one-pot, three-component, solvent-free synthesis of novel 6H-chromeno[3′,4′:5,6]pyrido[2,3-d]pyrimidine-triones under microwave irradiation

被引：3

作者：

Firoozpour, Loghman ^{[1
]}

Yahyavi, Hoda ^{[1
]}

Ejtemaei, Ramona ^{[2
]}

Moghimi, Setareh ^{[1
]}

Foroumadi, Alireza ^{[2
,3
]}

机构：

[1] Univ Tehran Med Sci, Drug Design & Dev Res Ctr, Inst Pharmaceut Sci TIPS, Tehran, Iran

[2] Univ Tehran Med Sci, Fac Pharm, Dept Med Chem, Tehran, Iran

[3] Kerman Univ Med Sci, Neurosci Res Ctr, Inst Neuropharmacol, Kerman, Iran

来源：

JOURNAL OF CHEMICAL RESEARCH | 2018年 / 12期

关键词：

multi-component reaction; green chemistry; 4-amino-2H-chromene-2-one; solvent-free conditions; microwave irradiation; MULTICOMPONENT SYNTHESIS; EFFICIENT; WATER;

D O I：

10.3184/174751918X15414289771620

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A green and efficient method for preparing novel heterocyclic systems is established through the reaction of differently substituted benzaldehydes, barbituric acid and 4-amino-2H-chromene-2-one undersolvent-free conditions. This method affords 6H-chromeno[3',4':5,6] pyrido[2,3-d]pyrimidine-trione derivatives in high yields and short reaction times.

引用

页码：604 / 607

页数：4

共 23 条

[1]

Abdolmohammadi S, 2013, COMB CHEM HIGH T SCR, V16, P150

[2] AN EFFICIENT ONE-POT THREE-COMPONENT SYNTHESIS OF HIGHLY FUNCTIONALIZED COUMARIN FUSED INDENODIHYDROPYRIDINE AND CHROMENO[4,3-b]QUINOLINE DERIVATIVES [J].

Ahmed, Naseem ;

Babu, B. Venkata ;

Singh, Sandeep ;

Mitrasinovic, Petar M. .

HETEROCYCLES, 2012, 85 (07) :1629-+

[3]

Anastas P. T., 2000, GREEN CHEM THEORY PR, P132

[4] Recent advances in solventless organic reactions: towards benign synthesis with remarkable versatility [J].

Cave, GWV ;

Raston, CL ;

Scott, JL .

CHEMICAL COMMUNICATIONS, 2001, (21) :2159-2169

[5] Fe3O4 nano-particles supported on cellulose as an efficient catalyst for the synthesis of pyrimido[4,5-b]quinolines in water [J].

Edjlali, Laden ;

Khanamiri, Rahim Hosseinzdeh ;

Abolhasani, Jafar .

MONATSHEFTE FUR CHEMIE, 2015, 146 (08) :1339-1342

[6] Synthesis and evaluation of novel quinazolinone-1,2,3-triazoles as inhibitors of lipoxygenase [J].

Farjadmand, Fatemeh ;

Arshadi, Hossein ;

Moghimi, Setareh ;

Nadri, Hamid ;

Moradi, Alireza ;

Eghtedari, Mohammad ;

Jafarpour, Farnaz ;

Mahdavi, Mohammad ;

Shafiee, Abbas ;

Foroumadi, Alireza .

JOURNAL OF CHEMICAL RESEARCH, 2016, (03) :188-191

[7] Synthesis and anti-acetylcholinesterase activity of N-[(indolyl)ethyl)-coumarin-yloxy)] alkanamides [J].

Ghanei-Nasab, Sarah ;

Nadri, Hamid ;

Moradi, Alireza ;

Marjani, Azam ;

Shabani, Shabnam ;

Firoozpour, Loghman ;

Moghimi, Setareh ;

Khoobi, Mehdi ;

Hadizadeh, Farzin ;

Foroumadi, Alireza .

JOURNAL OF CHEMICAL RESEARCH, 2017, (02) :120-123

[8] Aqua mediated indium(III) chloride catalyzed synthesis of fused pyrimidines and pyrazoles [J].

Khurana, Jitender M. ;

Chaudhary, Ankita ;

Nand, Bhaskara ;

Lumb, Anshika .

TETRAHEDRON LETTERS, 2012, 53 (24) :3018-3022

[9]

Kozlov N. G., 2007, RUSS J ORG CHEM+, V43, P433

[10]

Loupy A., 2012, MICROWAVES ORGANIC S, V2, P788

← 1 2 3 →